ReviewCell metabolism2014
Circuits controlling energy balance and mood: inherently intertwined or just complicated intersections?
Review in Cell metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Cannabinoid type-1 receptors in CaMKII neurons drive impulsivity in pathological eating behavior.Molecular metabolism · 2025Article
- Differential potentiation of odor aversion and yawning by melanocortin 4 receptor signaling in distinct regions of the ventral striatum.Frontiers in neuroscience · 2025Article
- Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice.Nature communications · 2021Observational
- The atypical antipsychotic risperidone targets hypothalamic melanocortin 4 receptors to cause weight gain.The Journal of experimental medicine · 2021Article
- Reciprocal control of obesity and anxiety-depressive disorder via a GABA and serotonin neural circuit.Molecular psychiatry · 2021Article
- Motivational valence is determined by striatal melanocortin 4 receptors.The Journal of clinical investigation · 2018Article
- A neural basis for antagonistic control of feeding and compulsive behaviors.Nature communications · 2018Article
- Effects of Estrogens on Central Nervous System Neurotransmission: Implications for Sex Differences in Mental Disorders.Progress in molecular biology and translational science · 2018Review
- Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.The Journal of clinical investigation · 2017Article
- Neural Circuit Mechanisms Underlying Emotional Regulation of Homeostatic Feeding.Trends in endocrinology and metabolism: TEM · 2017Review
- Taotie neurons regulate appetite in Drosophila.Nature communications · 2016Article
- Article
- Inter-organ communication and regulation of beta cell function.Diabetologia · 2016Review
- Central insulin signaling modulates hypothalamus-pituitary-adrenal axis responsiveness.Molecular metabolism · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Recent reports of adverse psychiatric events from seemingly different types of weight loss therapies highlight a previously underestimated overlap between CNS circuits that control energy balance and those that regulate mood. In this Perspective, we discuss a few potential brain sites where the homeostatic and the hedonic pathways may intersect and suggest that a better understanding of both pathways is necessary for the development of more effective and safer antiobesity therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.