ArticleJournal of the Academy of Nutrition and Dietetics2014
Cruciferous vegetable intake is inversely correlated with circulating levels of proinflammatory markers in women.
Article in Journal of the Academy of Nutrition and Dietetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 59 citations in OpenAlex.
- Effect of Cruciferous Vegetable Intake on Oxidative Stress Biomarkers: Differences by Breast Cancer Status.Cancer investigation · 2017Trial
- Associations between cruciferous vegetable intake and selected biomarkers among women scheduled for breast biopsies.Public health nutrition · 2016Trial
- Cruciferous vegetables have variable effects on biomarkers of systemic inflammation in a randomized controlled trial in healthy young adults.The Journal of nutrition · 2014Trial
- Systemic Lipid Peroxidation and Colorectal Cancer Risk: A Time-Varying Relationship.International journal of cancer · 2026Article
- A unified knowledge graph linking foodomics to chemical-disease networks and flavor profiles.NPJ science of food · 2026Article
- Adherence to the healthy nordic food index is associated with favorable obesity-related cardiometabolic risk factors among apparently healthy obese individuals.Scientific reports · 2025Article
- Quantile regression based method for characterizing risk-specific behavioral patterns in relation to longitudinal left-censored biomarker data collected from heterogeneous populations.Journal of applied statistics · 2025Article
- Association between the dietary index for gut microbiota and metabolic syndrome: the mediating role of the dietary inflammatory index.Frontiers in nutrition · 2025Article
- Associations between healthy food groups and platelet-activating factor, lipoprotein-associated phospholipase AEuropean journal of nutrition · 2024Article
- Article
- Review
- Influence of Nutrition and Physical Activity on Local and Systemic Inflammatory Signs in Experimentally Induced Gingivitis.Nutrients · 2023Article
- Early life exposure to broccoli sprouts confers stronger protection against enterocolitis development in an immunological mouse model of inflammatory bowel disease.bioRxiv : the preprint server for biology · 2023Article
- Prospective cohort study of broccoli consumption frequency and all-cause and cause-specific mortality risks.Frontiers in nutrition · 2023Article
- Article
- Poor Diet, Long Sleep, and Lack of Physical Activity Are Associated with Inflammation among Non-Demented Community-Dwelling Elderly.Healthcare (Basel, Switzerland) · 2022Article
- Use of a Highly Antioxidant Diet in the Regulation of Adipose Tissue Secretion in Patients after the BIB Procedure.Foods (Basel, Switzerland) · 2021Article
- Kale supplementation during high fat feeding improves metabolic health in a mouse model of obesity and insulin resistance.PloS one · 2021Article
- Pre-diagnosis Cruciferous Vegetables and Isothiocyanates Intake and Ovarian Cancer Survival: A Prospective Cohort Study.Frontiers in nutrition · 2021Article
- Relation of Fruits and Vegetables with Major Cardiometabolic Risk Factors, Markers of Oxidation, and Inflammation.Nutrients · 2019Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundHigher intakes of cruciferous vegetables or their constituents have been shown to lower inflammation in animal studies. However, evidence for this anti-inflammatory effect of cruciferous vegetable consumption in humans is scarce. OBJECTIVE/
designIn this cross-sectional analysis, we evaluated associations of vegetable intake with a panel of inflammatory and oxidative stress markers among 1,005 middle-aged Chinese women. Dietary intake of foods was assessed by a food frequency questionnaire.
resultsMultivariable-adjusted circulating concentrations of tumor necrosis factor-α (TNF-α), interlukin-1β (IL-1β), and IL-6 were lower among women with higher intakes of cruciferous vegetables. The differences in concentrations of inflammatory biomarkers between extreme quintiles of cruciferous vegetable intake were 12.66% for TNF-α (Ptrend=0.01), 18.18% for IL-1β (Ptrend=0.02), and 24.68% for IL-6 (Ptrend=0.02). A similar, but less apparent, inverse association was found for intakes of all vegetables combined but not for noncruciferous vegetables. Levels of the urinary oxidative stress markers F2-isoprostanes and their major metabolite, 2,3-dinor-5,6-dihydro-15-F2t-IsoP, were not associated with intakes of cruciferous vegetables or all vegetables combined.
conclusionsThis study suggests that the previously observed health benefits of cruciferous vegetable consumption may be partly associated with the anti-inflammatory effects of these vegetables.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.