Stem cell-based therapy for newborn lung and brain injury: feasible, safe, and the next therapeutic breakthrough?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Autologous cord blood cell infusion in preterm neonates safely reduces respiratory support duration and potentially preterm complications.Stem cells translational medicine · 2020
   Article
2. Use of Autologous Cord Blood Mononuclear Cells Infusion for the Prevention of Bronchopulmonary Dysplasia in Extremely Preterm Neonates: A Study Protocol for a Placebo-Controlled Randomized Multicenter Trial [NCT03053076].Frontiers in pediatrics · 2020
   Article
3. Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation.American journal of respiratory and critical care medicine · 2018
   Article
4. "Good things come in small packages": application of exosome-based therapeutics in neonatal lung injury.Pediatric research · 2018
   Review
5. Addressing the challenges of phenotyping pediatric pulmonary vascular disease.Pulmonary circulation · 2017
   Review
6. Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency.Frontiers in cardiovascular medicine · 2017
   Article
7. Lacrimal Gland Repair Using Progenitor Cells.Stem cells translational medicine · 2017
   Article
8. Stem Cells: Potential Therapy for Neonatal Injury?Clinics in perinatology · 2015
   Review
9. Stem cell therapy for bronchopulmonary dysplasia: bench to bedside translation.Journal of Korean medical science · 2015
   Review
10. Impaired pulmonary vascular development in bronchopulmonary dysplasia.Neonatology · 2015
    Review

Corrections and comments

• Comment on
  Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy.2014
• Comment on
  Mesenchymal stem cells for bronchopulmonary dysplasia: phase 1 dose-escalation clinical trial.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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