ArticleThe Journal of pediatrics2014
Effects of prenatal methamphetamine exposure on behavioral and cognitive findings at 7.5 years of age.
Article in The Journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effects of Prenatal Methamphetamine Exposure on the Developing Human Brain: A Systematic Review of Neuroimaging Studies.ACS chemical neuroscience · 2021Pooled it
- Prenatal Methamphetamine Exposure: Effects on Child Development–A Systematic Review.Deutsches Arzteblatt international · 2021Pooled it
- A Systematic Review and Meta-Analysis Investigating the Relationship between Exposures to Chemical and Non-Chemical Stressors during Prenatal Development and Childhood Externalizing Behaviors.International journal of environmental research and public health · 2020Pooled it
- Sex-specific effects of prenatal methamphetamine exposure on activity and blood pressure in aged offspring.Frontiers in behavioral neuroscience · 2026Article
- Amphetamine exposure during embryogenesis changes expression and function of the dopamine transporter in Caenorhabditis elegans offspring.Journal of neurochemistry · 2024Article
- MDPV (3,4-methylenedioxypyrovalerone) administered to mice during development of the central nervous system produces persistent learning and memory impairments.Pharmacological reports : PR · 2024Article
- Perinatal Psychoactive Substances Use: A Rising Perinatal Mental Health Concern.Journal of clinical medicine · 2023Review
- Morbidity through 3 Years of Age in Children of Women Using Methamphetamine during Pregnancy: A National Registry Study.European addiction research · 2023Article
- Daily, limited access to methamphetamine self-administration during pregnancy leads to increased methamphetamine sensitivity in adult offspring.Developmental psychobiology · 2023Article
- Maternal use of methamphetamine induces sex-dependent changes in myocardial gene expression in adult offspring.Physiological reports · 2022Article
- Methamphetamine Exposure During Development Causes Lasting Changes to Mesolimbic Dopamine Signaling in Mice.Cellular and molecular neurobiology · 2022Article
- Methamphetamine Use During the First or Second Half of Pregnancy Worsens Cardiac Ischemic Injury in Adult Female Offspring.Physiological research · 2022Article
- Prenatal Exposure to Methamphetamine Causes Vascular Dysfunction in Adult Male Rat Offspring.Frontiers in cardiovascular medicine · 2022Article
- Maternal Methamphetamine Exposure Influences Behavioral Sensitization and Nucleus Accumbens DNA Methylation in Subsequent Generation.Frontiers in pharmacology · 2022Article
- Can prenatal methamphetamine exposure be considered a good animal model for ADHD?Physiological research · 2021Article
- Adverse childhood experiences are associated with illicit drug use among pregnant women with middle to high socioeconomic status: findings from the All Our Families Cohort.BMC pregnancy and childbirth · 2021Article
- Effectiveness of Group Narrative Therapy on Depression, Quality of Life, and Anxiety in People with Amphetamine Addiction: A Randomized Clinical Trial.Iranian journal of medical sciences · 2020Article
- Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants.The EMBO journal · 2020Article
- A Validated Method for the Simultaneous Determination of Methamphetamine and 3,4-Methylenedioxy-International journal of analytical chemistry · 2020Article
- Gender Differences in the Outcome of Offspring Prenatally Exposed to Drugs of Abuse.Frontiers in behavioral neuroscience · 2020Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectiveTo examine child behavioral and cognitive outcomes after prenatal exposure to methamphetamine. STUDY
designWe enrolled 412 mother-infant pairs (204 methamphetamine-exposed and 208 unexposed matched comparisons) in the Infant Development, Environment, and Lifestyle study. The 151 children exposed to methamphetamine and 147 comparisons who attended the 7.5-year visit were included. Exposure was determined by maternal self-report and/or positive meconium toxicology. Maternal interviews assessed behavioral and cognitive outcomes using the Conners' Parent Rating Scale-Revised: Short Form.
resultsAfter adjusting for covariates, children exposed to methamphetamine had significantly higher cognitive problems subscale scores than comparisons and were 2.8 times more likely to have cognitive problems scores that were above average on the Conners' Parent Rating Scale-Revised: Short Form. No association between prenatal methamphetamine exposure and behavioral problems, measured by the oppositional, hyperactivity, and attention-deficit/hyperactivity disorder index subscales, were found.
conclusionsPrenatal methamphetamine exposure was associated with increased cognitive problems, which may affect academic achievement and lead to increased negative behavioral outcomes.
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