Caveats about QuantiFERON-TB gold in-tube testing for uveitis.

Kathryn L Pepple, Russell Van Gelder, Farzin Forooghian

Abstract readEditorialComment

In one paragraph

Article in American journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Ocular TB as the only manifestation of TB: diagnostic uncertainty and treatment thresholds.International ophthalmology · 2026
Review
Splenic tuberculosis and multifocal serpiginoid choroiditis.International ophthalmology · 2018
Article
What does IGRA testing add to the diagnosis of ocular tuberculosis? A Bayesian latent class analysis.BMC ophthalmology · 2017
Article
Structural changes of the choroid in sarcoid- and tuberculosis-related granulomatous uveitis.Eye (London, England) · 2015
Article
Serpiginoid choroiditis associated with presumed ocular tuberculosis.Taiwan journal of ophthalmology
Article

4 · The record

Corrections and comments

Comment on
Clinical manifestations of patients with intraocular inflammation and positive QuantiFERON-TB gold in-tube test in a country nonendemic for tuberculosis.2014

5 · Who and what money

Authors and funding

3 authors.

Kathryn L PeppleDepartment of Ophthalmology, University of Washington, Seattle, Washington.

Russell Van GelderDepartment of Ophthalmology, University of Washington, Seattle, Washington; Department of Pathology, University of Washington, Seattle, Washington; Department of Biological Structure, University of Washington, Seattle, Washington.

Farzin ForooghianDepartment of Ophthalmology & Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: farzin.forooghian@gmail.com.

Funding

Diversity and Dynamic Stability of the Ocular Surface MicrobiomeR01EY022038 · NEI · UNIVERSITY OF WASHINGTON · PI SHESTOPALOV, VALERY I, VAN GELDER, RUSSELL N. · 2012 to 2016

$3.2M

The role of the innate and adaptive immune system in a novel model of uveitK08EY023998 · NEI · UNIVERSITY OF WASHINGTON · PI PEPPLE, KATHRYN · 2014 to 2018

$1.1M

NEI NIH HHS 1K08EY023998NEI NIH HHS 1R01EY022038NEI NIH HHS K08 EY023998NEI NIH HHS R01 EY022038

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Interferon-gamma Release TestsChoroiditisFemaleHumansMaleRetinal VasculitisScleritisTuberculosis, OcularUveitis

Identifiers

PMID24630206

DOI10.1016/j.ajo.2013.12.021

PMCPMC4263814

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.