Evidence map›Paper›PMID 24629422›Full record

Observational studyGastrointestinal endoscopy2014

Boston Bowel Preparation Scale scores provide a standardized definition of adequate for describing bowel cleanliness.

Audrey H Calderwood, Paul C Schroy, David A Lieberman, Judith R Logan, Michael Zurfluh, Brian C Jacobson

4 registry-linked trialsAbstract readObservational Study
In one paragraph

Observational study in Gastrointestinal endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 96 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02976805 phase3completednot on this mapstarted 2017, after this paper: background citation

A Multi-centre Endoscopist Blinded Randomized Clinical Trial to Compare Two Bowel Preparations After a Colonoscopy With Inadequate Bowel Preparation

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2017 to 2020Enrolled196ConditionsColonoscopy, Bowel PreparationArms4L PegLyte + 15 mg bisacodyl, 6L PegLyte + 15 mg bisacodyl
NCT03247595 nacompletednot on this mapstarted 2017, after this paper: background citation

Efficacy of Magnesium Citrate Capsules in Colonoscopy Preparation: A Randomized, Investigator-blinded Non-inferiority Trial Using Polyethylene Glycol as the Active Control.

TypeinterventionalSponsorLifeBridge HealthRan2017 to 2020Enrolled62ConditionsColonoscopyArmsMagnesium Citrate Capsules, Polyethylene Glycol 3350, Dulcolax Tablets
NCT03650725 completednot on this mapstarted 2018, after this paper: background citation

Evaluation of Information Provided to Patients Provided About Bowel Preparation for Morning Colonoscopy

TypeobservationalSponsorHarminder SinghRan2018 to 2023Enrolled1,000ConditionsColonoscopy, Patient ComplianceArmsMandatory Split bowel preparation
NCT04482452 unknown statusnot on this mapstarted 2020, after this paper: background citation

Percentage Visualized Mucosa as a Marker for the Quality of Colonoscopy

TypeobservationalSponsorInsel Gruppe AG, University Hospital BernRan2020 to 2022Enrolled500ConditionsColonoscopyArmsColonoscopy
3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  4. Validated Scales for Colon Cleansing: A Systematic Review.The American journal of gastroenterology · 2016
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  19. The advantage of polyethylene glycol electrolyte solution combined with lactulose in patients with long interval preparation-to-colonoscopy.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Audrey H CalderwoodSection of Gastroenterology, Boston Medical Center, Boston, Massachusetts, USA.
Paul C SchroySection of Gastroenterology, Boston Medical Center, Boston, Massachusetts, USA.
David A LiebermanDivision of Gastroenterology, Oregon Health & Science University, Portland, Oregon, USA.
Judith R LoganDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, Oregon, USA.
Michael ZurfluhDivision of Gastroenterology, Oregon Health & Science University, Portland, Oregon, USA.
Brian C JacobsonSection of Gastroenterology, Boston Medical Center, Boston, Massachusetts, USA.

Funding

National Endoscopic Database of the Clinical Outcomes Research InitiativeU01DK057132 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI LIEBERMAN, DAVID A · 1999 to 2014
$12.7M
CORI: Consortium Expansion and Database EnhancementR33DK061778 · NIDDK · OREGON HEALTH AND SCIENCE UNIVERSITY · PI LIEBERMAN, DAVID A · 2002 to 2004
$1.4M
A Novel Colonoscopy Bowel Preparation Scale: Education, Validation, and UtilityK08DK090150 · NIDDK · BOSTON MEDICAL CENTER · PI CALDERWOOD, AUDREY HONG · 2011 to 2015
$711k
Colonoscopy in Rural Oregon Practice (CROP)R21CA131626 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LIEBERMAN, DAVID A · 2008 to 2009
$381k
NCI NIH HHS R21 CA131626NCI NIH HHS R21-CA131626NIDDK NIH HHS K08 DK090150NIDDK NIH HHS R33 DK061778NIDDK NIH HHS R33-DK61778-01NIDDK NIH HHS U01 DK057132PHS HHS K08-24674354
6 · The paper itself

Abstract

backgroundEstablishing a threshold of bowel cleanliness below which colonoscopies should be repeated at accelerated intervals is important, yet there are no standardized definitions for an adequate preparation.

objectiveTo determine whether Boston Bowel Preparation Scale (BBPS) scores could serve as a standard definition of adequacy.

designCross-sectional observational analysis of colonoscopy data from 36 adult GI endoscopy practices and prospective survey showing 4 standardized colonoscopy videos with varying degrees of bowel cleanliness.

settingThe Clinical Outcomes Research Initiative. PATIENTS: Average-risk patients attending screening colonoscopy.

interventionsColonoscopy. MAIN OUTCOME MEASUREMENTS: Recommended follow-up intervals among average-risk, screening colonoscopies without polyps stratified by BBPS scores.

resultsWe evaluated 2516 negative screening colonoscopies performed by 74 endoscopists. If the BBPS score was ≥2 in all 3 segments (N = 2295), follow-up was recommended in 10 years in 90% of cases. Examinations with total BBPS scores of 3 to 5 (N = 167) had variable recommendations. Follow-up within 1 year was recommended for 96% of examinations with total BBPS scores of 0 to 2 (N = 26). Similar results were noted among 167 participants in a video survey with pre-established BBPS scores. LIMITATIONS: Retrospective study.

conclusionBBPS scores correlate with endoscopist behavior regarding follow-up intervals for colonoscopy. A total BBPS score ≥6 and/or all segment scores ≥2 provides a standardized definition of adequate for 10-year follow-up, whereas total scores ≤2 indicate that a procedure should be repeated within 1 year. Future work should focus on finding consensus for management of examinations with total scores of 3 to 5.

Indexed as

CatharticsColonic PolypsColonoscopyCross-Sectional StudiesEarly Detection of CancerFemaleHumansMaleMiddle AgedPractice Patterns, Physicians'Preoperative CareProcess Assessment, Health CareProspective StudiesTime FactorsVideo RecordingCathartics

Identifiers

PMID24629422
PMCPMC4104141

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.