Evidence map›Paper›PMID 24629330›Full record

ArticleCell host & microbe2014

Is the intestinal goblet cell a major immune cell?

Malin E V Johansson, Gunnar C Hansson

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell host & microbe, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Infection of endemic chubParasitology · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Differentiated Epithelial Cells of the Gut.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  14. Review
  15. Article
  16. Review
  17. Colon mucus in colorectal neoplasia and beyond.World journal of gastroenterology · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Malin E V JohanssonDepartment of Medical Biochemistry, University of Gothenburg, Gothenburg, Sweden.
Gunnar C HanssonDepartment of Medical Biochemistry, University of Gothenburg, Gothenburg, Sweden. Electronic address: gunnar.hansson@medkem.gu.se.
University of Gothenburg · SE

Funding

The MUC2 Mucus Gel as an Innate Immune Mechanism that Inhibits InflammationU01AI095473 · NIAID · GOTEBORG UNIVERSITY · PI HANSSON, GUNNAR C., JOHANSSON, MALIN E.V. · 2011 to 2020
$2.6M
NIAID NIH HHS U01 AI095473
6 · The paper itself

Abstract

Recent reports indicate that both the inflammasome (Wlodarska et al., 2014) and autophagy (Patel et al., 2013) pathways in goblet cells control mucin secretion, defects in which are linked to difficulties in clearing pathogenic bacteria and maintaining intestinal homeostasis and control colitis.

Indexed as

AutophagyAnimalsColonGoblet CellsInflammasomesIntestinal MucosaMicrotubule-Associated ProteinsReactive Oxygen SpeciesReceptors, Cell SurfaceInflammasomesMicrotubule-Associated ProteinsReactive Oxygen SpeciesReceptors, Cell Surface

Identifiers

PMID24629330
PMCPMC4117991
OpenAlexW1996762292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.