ReviewCellular microbiology2014
Intracellular killing of bacteria: is Dictyostelium a model macrophage or an alien?
Review in Cellular microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
- Membrane microdomains are crucial forScience advances · 2026Article
- Cell-in-cell phenomena across the tree of life.Scientific reports · 2024Article
- Quantitative Analysis of the Inactivation Process of Internalized Bacteria in Dictyostelium Cells.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Predation-resistant Pseudomonas bacteria engage in symbiont-like behavior with the social amoeba Dictyostelium discoideum.The ISME journal · 2023Article
- Sequential action of antibacterial effectors in Dictyostelium discoideum phagosomes.Molecular microbiology · 2023Article
- On the origin of the functional versatility of macrophages.Frontiers in physiology · 2023Article
- The Ecology and Evolution of Amoeba-Bacterium Interactions.Applied and environmental microbiology · 2021Review
- Insight into the Lifestyle of AmoebaMicroorganisms · 2020Article
- Type 1 Fimbriae and Motility Play a Pivotal Role During Interactions of Salmonella typhimurium with Acanthamoeba castellanii (T4 Genotype).Current microbiology · 2020Article
- Transcriptional Responses ofFrontiers in microbiology · 2020Article
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- Secreted heme peroxidase fromThe Journal of biological chemistry · 2018Article
- Vps13F links bacterial recognition and intracellular killing in Dictyostelium.Cellular microbiology · 2017Article
- Ancient bacteria-amoeba relationships and pathogenic animal bacteria.PLoS biology · 2017Article
- Acanthamoeba castellanii is not be an adequate model to study human adenovirus interactions with macrophagic cells.PloS one · 2017Article
- Using the social amoeba Dictyostelium to study the functions of proteins linked to neuronal ceroid lipofuscinosis.Journal of biomedical science · 2016Review
- Vermamoeba vermiformis-Aspergillus fumigatus relationships and comparison with other phagocytic cells.Parasitology research · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Predation of bacteria by phagocytic cells was first developed during evolution by environmental amoebae. Many of the core mechanisms used by amoebae to sense, ingest and kill bacteria have also been conserved in specialized phagocytic cells in mammalian organisms. Here we focus on recent results revealing how Dictyostelium discoideum senses and kills non-pathogenic bacteria. In this model, genetic analysis of intracellular killing of bacteria has revealed a surprisingly complex array of specialized mechanisms. These results raise new questions on these processes, and challenge current models based largely on studies in mammalian phagocytes. In addition, recent studies suggest one additional level on complexity by revealing how Dictyostelium recognizes specifically various bacterial species and strains, and adapts its metabolism to process them. It remains to be seen to what extent mechanisms uncovered in Dictyostelium are also used in mammalian phagocytic cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.