Evidence map›Paper›PMID 24628687›Full record

ArticleNanomedicine (London, England)2014

Stable confinement of positron emission tomography and magnetic resonance agents within carbon nanotubes for bimodal imaging.

Brandon T Cisneros, Justin J Law, Michael L Matson, Ali Azhdarinia, Eva M Sevick-Muraca, Lon J Wilson

Open access · greenAbstract read
In one paragraph

Article in Nanomedicine (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
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  9. Evaluation of the Biodistribution of Serinolamide-Derivatized CNanomaterials (Basel, Switzerland) · 2020
    Article
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  12. Review
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  14. Review
  15. Encapsulation of α-Particle-Emitting 225Ac3+ Ions Within Carbon Nanotubes.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2015
    Article
  16. Article
  17. Nanoscale Radiotheranostics for Cancer Treatment: From Bench to Bedside.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Brandon T CisnerosDepartment of Chemistry & Richard E Smalley Institute for Nanoscale Science & Technology, Rice University, 1900 Rice Blvd, Houston, TX 77005, USA.
Justin J Law
Michael L Matson
Ali Azhdarinia
Eva M Sevick-Muraca
Lon J Wilson
Brown Foundation · USThe University of Texas Health Science Center at Houston · USThe University of Texas MD Anderson Cancer Center · US

Funding

Task Specific Project 4U54CA136404 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SEVICK, EVA M. · 2008 to 2012
$5.1M
NCI NIH HHS U54 CA136404
6 · The paper itself

Abstract

aimsSimultaneous positron emission tomography/MRI has recently been introduced to the clinic and dual positron emission tomography/MRI probes are rare and of growing interest. We have developed a strategy for producing multimodal probes based on a carbon nanotube platform without the use of chelating ligands. MATERIALS &

methodsGd(3+) and (64)Cu(2+) ions were loaded into ultra-short single-walled carbon nanotubes by sonication. Normal, tumor-free athymic nude mice were injected intravenously with the probe and imaged over 48 h. RESULTS &

conclusionThe probe was stable for up to 24 h when challenged with phosphate-buffered saline and mouse serum. Positron emission tomography imaging also confirmed the stability of the probe in vivo for up to 48 h. The probe was quickly cleared from circulation, with enhanced accumulation in the lungs. Stable encapsulation of contrast agents within ultra-short single-walled carbon nanotubes represents a new strategy for the design of advanced imaging probes with variable multimodal imaging capabilities.

Indexed as

Contrast MediaAnimalsHumansMagnetic Resonance ImagingMiceMultimodal ImagingNanotubes, CarbonPositron-Emission TomographyContrast MediaNanotubes, Carboncarbon nanotubecontrast agentMRImultimodal imagingpositron emission tomography

Identifiers

PMID24628687
PMCPMC4167560
OpenAlexW2106951935

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.