Evidence map›Paper›PMID 24628496›Full record

ReviewJournal of agricultural and food chemistry2014

Accumulation of high-value lipids in single-cell microorganisms: a mechanistic approach and future perspectives.

Luis A Garay, Kyria L Boundy-Mills, J Bruce German

Abstract readReview
In one paragraph

Review in Journal of agricultural and food chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. MarinePharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Sustainable Lipid Production withMicroorganisms · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Review
  10. Article
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  13. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luis A GarayDepartment of Food Science and Technology, University of California , Davis, One Shields Avenue, Davis California 95616-8598, United States.
Kyria L Boundy-Mills
J Bruce German

Funding

West Coast Central Comprehensive Metabolomics Resource Core (WC3MRC)U24DK097154 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2012 to 2017
$9.9M
Necrotizing Enterocolitis: Prevention and PredictionR01HD059127 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEBRILLA, CARLITO B, MILLS, DAVID ANDREW · 2008 to 2012
$3.1M
Mechanism of Activation of Probiotic Bifidobacteria by Prebiotic Milk GlycansR01AT007079 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERMAN, BRUCE, LEBRILLA, CARLITO B · 2012 to 2016
$2.2M
Oligosaccharides as antimicrobials and prebioticsR01HD065122 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2010 to 2013
$1.8M
Structures, Functions, & Genetic Diversity of Oligosaccharides in MilkR01HD061923 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEBRILLA, CARLITO B · 2009 to 2013
$1.6M
Activation of Host-Probiotic Communication by Prebiotic Milk OligosaccharidesR21AT006180 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MILLS, DAVID ANDREW, RAYBOULD, HELEN E · 2011 to 2012
$421k
NCCIH NIH HHS R01AT007079NCCIH NIH HHS R21AT006180NICHD NIH HHS R01HD059127NICHD NIH HHS R01HD061923NICHD NIH HHS R01HD065122NIDDK NIH HHS U24 DK097154
6 · The paper itself

Abstract

In recent years attention has been focused on the utilization of microorganisms as alternatives for industrial and nutritional applications. Considerable research has been devoted to techniques for growth, extraction, and purification of high-value lipids for their use as biofuels and biosurfactants as well as high-value metabolites for nutrition and health. These successes argue that the elucidation of the mechanisms underlying the microbial biosynthesis of such molecules, which are far from being completely understood, now will yield spectacular opportunities for industrial scale biomolecular production. There are important additional questions to be solved to optimize the processing strategies to take advantage of the assets of microbial lipids. The present review describes the current state of knowledge regarding lipid biosynthesis, accumulation, and transport mechanisms present in single-cell organisms, specifically yeasts, microalgae, bacteria, and archaea. Similarities and differences in biochemical pathways and strategies of different microorganisms provide a diverse toolset to the expansion of biotechnologies for lipid production. This paper is intended to inspire a generation of lipid scientists to insights that will drive the biotechnologies of microbial production as uniquely enabling players of lipid biotherapeutics, biofuels, biomaterials, and other opportunity areas into the 21st century.

Indexed as

BacteriaBiofuelsBiotechnologyLipidsMicroalgaeYeastsBiofuelsLipids

Identifiers

PMID24628496
PMCPMC3983371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.