ReviewJournal of neurogenetics
Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells.
Review in Journal of neurogenetics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 58 citations in OpenAlex.
- Impact of perfusion on neuronal development in human derived neuronal networks.APL bioengineering · 2024Article
- Toward the use of novel alternative methods in epilepsy modeling and drug discovery.Frontiers in neurology · 2023Review
- Reprogramming of adult human dermal fibroblasts to induced dorsal forebrain precursor cells maintains aging signatures.Frontiers in cellular neuroscience · 2023Article
- Article
- Human-Induced Pluripotent Stem Cell Technology: Toward the Future of Personalized Psychiatry.Journal of personalized medicine · 2022Review
- Long-term culture of SH-SY5Y neuroblastoma cells in the absence of neurotrophins: A novel model of neuronal ageing.Journal of neuroscience methods · 2021Article
- Controlling properties of human neural progenitor cells using 2D and 3D conductive polymer scaffolds.Scientific reports · 2019Article
- Recapitulating kidney development: Progress and challenges.Seminars in cell & developmental biology · 2019Review
- Differentiation of Human Induced Pluripotent Stem Cells (iPSCs) into an Effective Model of Forebrain Neural Progenitor Cells and Mature Neurons.Bio-protocol · 2019Article
- Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons.Scientific reports · 2018Article
- A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells.Cerebellum (London, England) · 2018Article
- 2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling.Molecular neurodegeneration · 2018Review
- Shared effects of DISC1 disruption and elevated WNT signaling in human cerebral organoids.Translational psychiatry · 2018Article
- Astrocyte-enriched feeder layers from cryopreserved cells support differentiation of spontaneously active networks of human iPSC-derived neurons.Journal of neuroscience methods · 2018Article
- Reproducible and efficient generation of functionally active neurons from human hiPSCs for preclinical disease modeling.Stem cell research · 2018Article
- Cell-Biological Requirements for the Generation of Dentate Gyrus Granule Neurons.Frontiers in cellular neuroscience · 2018Review
- A Microfluidic Platform for the Characterisation of CNS Active Compounds.Scientific reports · 2017Article
- Three-Dimensional Hyaluronic Acid Hydrogel-Based Models for In Vitro Human iPSC-Derived NPC Culture and Differentiation.Journal of materials chemistry. B · 2017Article
- Back and forth in time: Directing age in iPSC-derived lineages.Brain research · 2017Review
- Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence.The European journal of neuroscience · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Seven years have passed since the initial report of the generation of induced pluripotent stem cells (iPSCs) from adult human somatic cells, and in the intervening time the field of neuroscience has developed numerous disease models using this technology. Here, we review progress in the field and describe both the advantages and potential pitfalls of modeling neurodegenerative and neurodevelopmental diseases using this technology. We include tables with information on neural differentiation protocols and studies that developed human iPSC lines to model neurological diseases. We also discuss how one can: investigate effects of genetic mutations with iPSCs, examine cell fate-specific phenotypes, best determine the specificity of a phenotype, and bring in vivo relevance to this in vitro technique.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.