Evidence map›Paper›PMID 24628401›Full record

ReviewActa paediatrica (Oslo, Norway : 1992)2014

Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo.

Christine M O'Brien, Elizabeth Vargis, Bibhash C Paria, Kelly A Bennett, Anita Mahadevan-Jansen, Jeff Reese

Abstract readReview
In one paragraph

Review in Acta paediatrica (Oslo, Norway : 1992), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. New techniques in evaluation of the cervix.Seminars in perinatology · 2017
    Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christine M O'BrienDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Elizabeth Vargis
Bibhash C Paria
Kelly A Bennett
Anita Mahadevan-Jansen
Jeff Reese

Funding

TRAINING GRANT IN MECHANISMS OF VASCULAR DISEASET32HL007751 · NHLBI · VANDERBILT UNIVERSITY · PI BOCK, PAUL E · 1994 to 2014
$6.6M
Hamster: A Unique Model for Studying ImplantationR01HD044741 · NICHD · VANDERBILT UNIVERSITY · PI PARIA, BIBHASH CHANDRA · 2004 to 2014
$2.9M
Diagnosis of Cervical &Vulvar PrecancersR01CA095405 · NCI · VANDERBILT UNIVERSITY · PI MAHADEVAN-JANSEN, ANITA · 2002 to 2012
$2.4M
Detecting biochemical changes in the pregnant mouse cervix by Raman spectroscopyR01HD081121 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MAHADEVAN-JANSEN, ANITA, REESE, JOHN JEFFREY · 2014 to 2018
$1.9M
NCI NIH HHS R01 CA095405NCI NIH HHS R01-CA-095405NHLBI NIH HHS T32 HL007751NHLBI NIH HHS T32-HL-7751-15NICHD NIH HHS HD 044741NICHD NIH HHS R01 HD044741NICHD NIH HHS R01 HD081121
6 · The paper itself

Abstract

unlabelledThe molecular changes that occur with cervical remodelling during pregnancy are not completely understood. This study reviews Raman spectroscopy, an optical technique for detecting changes in the pregnant cervix, and reports preliminary studies on cervical remodelling in mice that suggest that the technique provides advantages over other methods.

conclusionRaman spectroscopy is sensitive to biochemical changes in the pregnant cervix and has high potential as a tool for detecting premature cervical remodelling in pregnant women.

Indexed as

Cervical RipeningSpectrum Analysis, RamanAnimalsCervix UteriFemaleHumansPregnancyUterine Cervical DiseasesCervical remodellingCervixParturitionPregnancyPreterm birth

Identifiers

PMID24628401
PMCPMC4048629

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.