Evidence map›Paper›PMID 24628328›Full record

ReviewAnnals of the New York Academy of Sciences2014

The dynamic lives of macrophage and dendritic cell subsets in atherosclerosis.

Parésa L Taghavie-Moghadam, Matthew J Butcher, Elena V Galkina

Abstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Yangyin Qingre Huoxue Method in Traditional Chinese Medicine Ameliorates Atherosclerosis in ApoEEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Flow Cytometric Analysis of Immune Cells Within Murine Aorta.Methods in molecular biology (Clifton, N.J.) · 2015
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Parésa L Taghavie-MoghadamDepartment of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia.
Matthew J Butcher
Elena V Galkina

Funding

Role of the Interleukin12/STAT4 Pathway in Insulin Resistance and AtherosclerosisR01HL112605 · NHLBI · EASTERN VIRGINIA MEDICAL SCHOOL · PI NADLER, JERRY L. · 2012 to 2016
$2.0M
T cell plasticity in atherosclerosisR01HL107522 · NHLBI · EASTERN VIRGINIA MEDICAL SCHOOL · PI GALKINA, ELENA V · 2011 to 2015
$1.8M
NHLBI NIH HHS HL107522NHLBI NIH HHS HL112605 02S1NHLBI NIH HHS R01 HL107522NHLBI NIH HHS R01 HL112605
6 · The paper itself

Abstract

Atherosclerosis, the major pathological process through which arterial plaques are formed, is a dynamic chronic inflammatory disease of large- and medium-sized arteries in which the vasculature, lipid metabolism, and the immune system all play integral roles. Both the innate and adaptive immune systems are involved in the development and progression of atherosclerosis but myeloid cells represent the major component of the burgeoning atherosclerotic plaque. Various myeloid cells, including monocytes, macrophages (MΦs), and dendritic cells (DCs) can be found within the healthy and atherosclerotic arterial wall, where they can contribute to or regulate inflammation. However, the precise behaviors and functions of these cells in situ are still active areas of investigation that continue to yield exciting and surprising new data. Here, we review recent progress in understanding of the complex biology of MΦs and DCs, focusing particularly on the dynamic regulation of these subsets in the arterial wall and novel, emerging functions of these cells during atherogenesis.

Indexed as

Adaptive ImmunityAnimalsAtherosclerosisDendritic CellsHumansMacrophagesatherosclerosisdendritic cellimmune responseinflammationmacrophage

Identifiers

PMID24628328
PMCPMC4101092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.