Evidence map›Paper›PMID 24627714›Full record

ReviewBiochemia medica2014

The importance of implementing safe sharps practices in the laboratory setting in Europe.

Gabriella De Carli, Dominique Abiteboul, Vincenzo Puro

Abstract readReview
In one paragraph

Review in Biochemia medica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Surveillance of laboratory exposures to human pathogens and toxins, Canada, 2024.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  3. Article
  4. Healthcare Waste-A Serious Problem for Global Health.Healthcare (Basel, Switzerland) · 2023
    Review
  5. Temporal trends in occupational accidents involving exposure to biological material in Brazil, 2010 to 2016.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT · 2021
    Article
  6. Article
  7. Article
  8. Surveillance of laboratory exposures to human pathogens and toxins: Canada 2017.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2018
    Article
  9. Errors in the Extra-Analytical Phases of Clinical Chemistry Laboratory Testing.Indian journal of clinical biochemistry : IJCB · 2018
    Article
  10. Article
  11. Article
  12. Surveillance of laboratory exposures to human pathogens and toxins: Canada 2016.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2017
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gabriella De CarliInfezioni Emergenti e Riemergenti e Centro di Riferimento AIDS, Department of Epidemiology and Pre-Clinical Research, National Institute for Infectious Diseases L. Spallanzani IRCCS, Rome, Italy.
Dominique AbiteboulGroupe d'Etude sur le Risque d'Exposition au Sang (GERES), Université Paris Diderot, Hôpital Bichat-Claude Bernard, Paris, France.
Vincenzo PuroInfezioni Emergenti e Riemergenti e Centro di Riferimento AIDS, Department of Epidemiology and Pre-Clinical Research, National Institute for Infectious Diseases L. Spallanzani IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare workers are at risk of sharps injuries and subsequent infection from more than 40 bloodborne pathogens or species. Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) together account for the vast majority of cases. The Directive 2010/32/EU "Prevention from sharp injuries in the hospital and healthcare sector", issued to protect workers from these risks, requires an integrated approach to prevention including awareness-raising, education, training, elimination of unnecessary needles, safe procedures for sharps use and disposal, banning of recapping, vaccination, use of personal protective equipment, provision of safety-engineered devices, and appropriate surveillance, monitoring, response and follow-up. As laboratories represent a high-risk setting both in the preanalytical and analytical phase, we reviewed accidents and prevention in this setting in the light of the new legislation. Phlebotomy is the procedure carrying the highest risk of exposure and infection, involved in 30-50% of HIV and HCV cases detected in nationwide systems following accidental blood exposures implemented since the 1990s in Italy and France. In laboratories, problems in the management of sharps containers, recapping, needle disassembly by hand and blood transfer from syringes into tubes were observed and accounted for two-thirds of injuries. These accidents could be reduced through education and monitoring of behaviours, and introduction of medical devices incorporating safety-engineered protection mechanisms with appropriate training. Laboratory staff should be immunized against HBV, and know policies and procedures for the post-exposure management and prophylaxis. The management commitment to safety is crucial to ensure the necessary support to these changes.

Indexed as

Communicable DiseasesEuropeHealth PersonnelHumansLaboratoriesNeedlestick InjuriesOccupational DiseasesOccupational ExposureRisk Factorsaccident preventionbloodborne pathogenslaboratoriesneedlestick injuriesoccupational exposure

Identifiers

PMID24627714
PMCPMC3936965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.