ArticleJournal of the American Heart Association2014
Interaction of inflammation, hyperuricemia, and the prevalence of hypertension among adults free of metabolic syndrome: NHANES 2009-2010.
Article in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 63 citations in OpenAlex.
- Effect of vitamin C and hesperidin on serum uric acid concentrations in healthy adults with high uric acid levels: the randomized controlled 'HesperidrinC trial'.European journal of nutrition · 2026Trial
- Interaction and Joint Effects of Inflammation and Triglyceride-Glucose (TyG) Index on Hyperuricemia Risk and the Mediating Role of TyG: A Cross-Sectional Study.Endocrinology, diabetes & metabolism · 2026Article
- The relationship among inflammatory biomarkers, hyperuricemia and chronic kidney disease: analysis of the NHANES 2015-2020.Renal failure · 2025Article
- Association between organophosphate esters exposure and the prevalence of hyperuricemia in US adults from NHANES 2011-2016.Scientific reports · 2025Article
- Systemic inflammation in asymptomatic hyperuricaemia with sonographic crystal deposits, including a comparison with normouricaemia and gout.Rheumatology (Oxford, England) · 2025Article
- Association between oral health and hyperuricemia in Korean adults: Korea National Health and Nutrition Examination Survey 2016-2019.The Korean journal of internal medicine · 2024Article
- Associations between hyperuricemia and ultrasound-detected knee synovial abnormalities in middle-aged and older population: a cross-sectional study.Journal of orthopaedic surgery and research · 2024Article
- Comparison Between Early-Onset and Common Gout: A Systematic Literature Review.Rheumatology and therapy · 2023Review
- Cardiovascular protection by SGLT2 inhibitors - Do anti-inflammatory mechanisms play a role?Molecular metabolism · 2022Review
- Concurrent presence of high serum uric acid and inflammation is associated with increased incidence of type 2 diabetes mellitus in Korean adult population.Scientific reports · 2022Article
- The elevated visceral adiposity index increases the risk of hyperuricemia in Chinese hypertensive patients: A cross-sectional study.Frontiers in endocrinology · 2022Article
- Clinical Effect of the Guizhi Shaoyao Zhimu Decoction in the Treatment of Hyperuricemia.BioMed research international · 2022Article
- Association between serum uric acid and depressive symptoms stratified by low-grade inflammation status.Scientific reports · 2021Article
- Early onset of hyperuricemia is associated with increased cardiovascular disease and mortality risk.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Article
- Characteristics, Comorbidities, and Potential Consequences of Uncontrolled Gout: An Insurance-Claims Database Study.Rheumatology and therapy · 2021Article
- Acupuncture to treat asymptomatic hyperuricemia: A protocol for systematic review and meta-analysis of randomized controlled trials.Medicine · 2021Article
- Prevalence of Hyperuricemia and the Use of Allopurinol in Older Poles-Results from a Population-Based PolSenior Study.International journal of environmental research and public health · 2021Article
- Hyperuricemia and Hypertension, Coronary Artery Disease, Kidney Disease: From Concept to Practice.International journal of molecular sciences · 2020Review
- C-reactive protein and incident hypertension in a worksite population of Japanese men.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- The risk of clinically diagnosed gout by serum urate levels: results from 30 years follow-up of the Malmö Preventive Project cohort in southern Sweden.Arthritis research & therapy · 2018Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperuricemia and markers of inflammation are correlated with the risk for hypertension. Whether hyperuricemia has any impact on the association between C-reactive protein (CRP) and hypertension is not known. METHODS AND
resultsWe analyzed cross-sectional data from the National Health and Nutrition Examination Survey, 2009-2010, using ordinary least squares and logistic regression models. Those who met the criteria for metabolic syndrome, had self-reported gout, or were <20 years old were excluded. For each 1-SD increase in serum urate, the serum CRP concentration was 20% higher in unadjusted linear regression models and 13% higher in multivariable linear regression models, after accounting for the effects of age, sex, race, socioeconomic and educational strata, renal function, lipids, smoking, and body mass index. In multivariable models adjusting for the same covariates, hyperuricemia was associated with hypertension with an odds ratio of 2.21 (1.71 to 2.85). When analyzed separately, this was observed in men and women. In multivariable analyses of the overall sample, elevated CRP levels were not associated with hypertension.
conclusionsAmong adults free of metabolic syndrome, elevated uric acid, but not elevated CRP, is independently associated with prevalent hypertension.
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