Evidence map›Paper›PMID 24626410›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo

Effect of Bifidobacterium animalis on mice infected with Strongyloides venezuelensis.

Teresa Cristina Goulart Oliveira-Sequeira, Érica Boarato David, Cláudia Ribeiro, Semíramis Guimarães, Ana Paula Batista Masseno, Satie Katagiri, Julio Lopes Sequeira

Open access · diamondAbstract read
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 52 citations in OpenAlex.

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  5. Immuno-modulatory Effects of InactivatedAdvanced biomedical research · 2023
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  15. Probiotics for the Control of Helminth Zoonosis.Journal of veterinary medicine · 2018
    Review
  16. Review
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Teresa Cristina Goulart Oliveira-SequeiraParasitology Department, Institute of Bioscience, São Paulo State University (UNESP), 18618-000BotucatuSP, Brazil, Parasitology Department, Institute of Bioscience, São Paulo State University (UNESP), 18618-000 Botucatu, SP, Brazil.
Érica Boarato DavidParasitology Department, Institute of Bioscience, São Paulo State University (UNESP), 18618-000BotucatuSP, Brazil, Parasitology Department, Institute of Bioscience, São Paulo State University (UNESP), 18618-000 Botucatu, SP, Brazil.
Cláudia RibeiroCollege of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), 18618-000BotucatuSP, Brazil, College of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), 18618-000 Botucatu, SP, Brazil.
Semíramis GuimarãesParasitology Department, Institute of Bioscience, São Paulo State University (UNESP), 18618-000BotucatuSP, Brazil, Parasitology Department, Institute of Bioscience, São Paulo State University (UNESP), 18618-000 Botucatu, SP, Brazil.
Ana Paula Batista MassenoCollege of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), 18618-000BotucatuSP, Brazil, College of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), 18618-000 Botucatu, SP, Brazil.
Satie KatagiriCollege of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), 18618-000BotucatuSP, Brazil, College of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), 18618-000 Botucatu, SP, Brazil.
Julio Lopes SequeiraCollege of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), 18618-000BotucatuSP, Brazil, College of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), 18618-000 Botucatu, SP, Brazil.
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The administration of viable Bifidobacterium animalis was tested to induce resistance against Strongyloides venezuelensis infection in mice. Effects on parasite burden, worm length, egg output, and intestinal mucosal histology were evaluated. The oral administration of B. animalis, strain 04450B, starting 14 days before the inoculation of nematode larvae significantly decreased the worm burden and egg output. In probiotic treated animals, the percent reduction of adult worms in the intestine was of 33% and the reduction of egg production was of 21%, compared with those of the control group. The duodenum villous height and villous/crypt ratio were significantly higher in probiotic-treated mice, indicating that this group could be experiencing less intestinal damage. The present findings revealed that the administration of B. animalis for the amelioration of host response to nematode infections is biologically plausible and could have some potential for impacting public health. Meanwhile, further study is needed to delineate the nature and identity of the factor(s) involved in these beneficial effects.

Indexed as

BifidobacteriumAnimalsFecesIntestinal Diseases, ParasiticIntestinal MucosaMiceMice, Inbred BALB CParasite Egg CountProbioticsStrongyloidesStrongyloidiasis

Identifiers

PMID24626410
PMCPMC4085849
OpenAlexW2067509204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.