ArticlePloS one2014
The multiple strategies of an insect herbivore to overcome plant cyanogenic glucoside defence.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 72 citations in OpenAlex.
- Plant cyanogenic glycosides: from structure to properties and potential applications.Frontiers in plant science · 2025Review
- Feeding and Growth Response of Fall ArmywormInsects · 2024Article
- Plant Cyanogenic-Derived Metabolites and Herbivore Counter-Defences.Plants (Basel, Switzerland) · 2024Review
- UHPLC-MS/MS Analysis of the Accumulation and Excretion of Steroidal Glycoalkaloids Consumed by Potato Tuber Moth (Insects · 2022Article
- β-Cyanoalanine synthase protects mites against Arabidopsis defenses.Plant physiology · 2022Article
- Hydroxynitrile lyase defends Arabidopsis against Tetranychus urticae.Plant physiology · 2022Article
- Unique metabolism of different glucosinolates in larvae and adults of a leaf beetle specialised on Brassicaceae.Scientific reports · 2022Article
- Development of plant systemic resistance by beneficial rhizobacteria: Recognition, initiation, elicitation and regulation.Frontiers in plant science · 2022Review
- Hijacking the Mustard-Oil Bomb: How a Glucosinolate-Sequestering Flea Beetle Copes With Plant Myrosinases.Frontiers in plant science · 2021Article
- Glucosinolate Abundance and Composition in Brassicaceae Influence Sequestration in a Specialist Flea Beetle.Journal of chemical ecology · 2020Article
- Nitric Oxide, an Essential Intermediate in the Plant-Herbivore Interaction.Frontiers in plant science · 2020Article
- Identification and evolution of glucosinolate sulfatases in a specialist flea beetle.Scientific reports · 2019Article
- Molecular identification and characterization of rhodaneses from the insect herbivore Pieris rapae.Scientific reports · 2018Article
- Review
- Article
- Plant Defensive β-Glucosidases Resist Digestion and Sustain Activity in the Gut of a Lepidopteran Herbivore.Frontiers in plant science · 2018Article
- Article
- Spatial separation of the cyanogenic β-glucosidase ZfBGD2 and cyanogenic glucosides in the haemolymph ofRoyal Society open science · 2017Article
- A Cyanide-Induced 3-Cyanoalanine Nitrilase in the Cyanide-Assimilating Bacterium Pseudomonas pseudoalcaligenes Strain CECT 5344.Applied and environmental microbiology · 2017Article
- Pesticide stress on plants negatively affects parasitoid fitness through a bypass of their phytophage hosts.Ecotoxicology (London, England) · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyanogenic glucosides (CNglcs) are widespread plant defence compounds that release toxic hydrogen cyanide by plant β-glucosidase activity after tissue damage. Specialised insect herbivores have evolved counter strategies and some sequester CNglcs, but the underlying mechanisms to keep CNglcs intact during feeding and digestion are unknown. We show that CNglc-sequestering Zygaena filipendulae larvae combine behavioural, morphological, physiological and biochemical strategies at different time points during feeding and digestion to avoid toxic hydrolysis of the CNglcs present in their Lotus food plant, i.e. cyanogenesis. We found that a high feeding rate limits the time for plant β-glucosidases to hydrolyse CNglcs. Larvae performed leaf-snipping, a minimal disruptive feeding mode that prevents mixing of plant β-glucosidases and CNglcs. Saliva extracts did not inhibit plant cyanogenesis. However, a highly alkaline midgut lumen inhibited the activity of ingested plant β-glucosidases significantly. Moreover, insect β-glucosidases from the saliva and gut tissue did not hydrolyse the CNglcs present in Lotus. The strategies disclosed may also be used by other insect species to overcome CNglc-based plant defence and to sequester these compounds intact.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.