Trial reportJournal of perinatology : official journal of the California Perinatal Association2014
Peripherally inserted central venous catheters: frequency of complications in premature newborn depends on the insertion site.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Central Lines and Their Complications in Neonates: A Case Report and Literature Review.Children (Basel, Switzerland) · 2023Review
- Role of a radiopaque agent and surveillance radiographs for peripherally inserted central catheters in newborn infants.Pediatric radiology · 2023Article
- A review of neonatal peripherally inserted central venous catheters in extremely or very low birthweight infants based on a 3-year clinical practice: Complication incidences and risk factors.Frontiers in pediatrics · 2022Article
- Article
- Risk factors for peripherally inserted central catheter complications in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Umbilical Venous Catheters and Peripherally Inserted Central Catheters: Are They Equally Safe in VLBW Infants? A Non-Randomized Single Center Study.Medicina (Kaunas, Lithuania) · 2019Observational
- Application of peripherally inserted central catheters in critically ill newborns experience from a neonatal intensive care unit.Medicine · 2019Article
- Central line-associated bloodstream infections in neonates.Korean journal of pediatrics · 2019Article
- The axillary vein and its tributaries are not in the mirror image of the axillary artery and its branches.PloS one · 2019Article
- Risk Factors Related to Peripherally Inserted Central Venous Catheter Nonselective Removal in Neonates.BioMed research international · 2018Article
- Indications and outcomes for tunneled central venous line placement via the axillary vein in children.Pediatric surgery international · 2017Article
- Article
- Peripherally inserted central catheters optimize nutrient intake in moderately preterm infants.Pediatric research · 2016Article
- Challenges Associated with Route of Administration in Neonatal Drug Delivery.Clinical pharmacokinetics · 2016Review
- Prediction of Nonelective Central Venous Catheter Removal in Medically Complex Neonates.Pediatric quality & safetyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe use of peripherally inserted central venous catheters (PICC lines) has reduced the mortality and morbidity of premature newborns. The usual sites of insertion are the veins in the upper arms but other locations are being used as well. STUDY
designTo examine whether using the axillary vein as a site of insertion of a PICC line affects the frequency of complications. Our study has a clinical trial design. A total of 62 neonates that had a PICC line inserted were recruited and randomly divided equally in two groups: in Group A (mean birth weight, standard deviation (s.d.)=1353 (142) g), the PICC line was inserted through the axillary vein, and in Group B (birth weight=1308 (112) g), the PICC line was inserted in other sites further from the axillary vein. The outcomes measured were the total PICC line-related complications, the reason for removing the catheter, the number of total attempts until successful insertion and the mean duration of stay of the catheter. The likelihood of having an adverse outcome was assessed with Mantel-Haenszel odds ratio (OR).
resultsPremature neonates with axillary PICC lines were 12 times less likely to have line-related complications (inflammation, blockage, edema, infection) as compared with any other site of insertion (OR= 95%, confidence interval (CI)=0.10 (0.01 to 0.8)) and they were seven times more likely to have the PICC line removed because they achieved full enteral nutrition as compared with the other causes (OR 95%, confidence interval (CI)=10.35 (4.88 to 21.96)). There was no statistical difference between the two groups in the number of attempts until successful PICC line insertion (P=0.667) and the mean duration of stay of the PICC line (P=0.97).
conclusionThe use of the axillary vein as a site of insertion of a PICC line was correlated with significantly less complications in premature newborns as opposed to the other sites of insertion.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.