Evidence map›Paper›PMID 24625221›Full record

ArticleRadiation oncology (London, England)2014

Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy.

Akihiro Haga, Taiki Magome, Shigeharu Takenaka, Toshikazu Imae, Akira Sakumi, Akihiro Nomoto, Hiroshi Igaki, Kenshiro Shiraishi, Hideomi Yamashita, Kuni Ohtomo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Akihiro HagaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan. haga-haga@umin.ac.jp.
Taiki Magome
Shigeharu Takenaka
Toshikazu Imae
Akira Sakumi
Akihiro Nomoto
Hiroshi Igaki
Kenshiro Shiraishi
Hideomi Yamashita
Kuni Ohtomo
Keiichi Nakagawa
University of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report the result of independent absorbed-dose calculations based on a Monte Carlo (MC) algorithm in volumetric modulated arc therapy (VMAT) for various treatment sites. METHODS AND MATERIALS: All treatment plans were created by the superposition/convolution (SC) algorithm of SmartArc (Pinnacle V9.2, Philips). The beam information was converted into the format of the Monaco V3.3 (Elekta), which uses the X-ray voxel-based MC (XVMC) algorithm. The dose distribution was independently recalculated in the Monaco. The dose for the planning target volume (PTV) and the organ at risk (OAR) were analyzed via comparisons with those of the treatment plan.Before performing an independent absorbed-dose calculation, the validation was conducted via irradiation from 3 different gantry angles with a 10- × 10-cm2 field. For the independent absorbed-dose calculation, 15 patients with cancer (prostate, 5; lung, 5; head and neck, 3; rectal, 1; and esophageal, 1) who were treated with single-arc VMAT were selected. To classify the cause of the dose difference between the Pinnacle and Monaco TPSs, their calculations were also compared with the measurement data.

resultIn validation, the dose in Pinnacle agreed with that in Monaco within 1.5%. The agreement in VMAT calculations between Pinnacle and Monaco using phantoms was exceptional; at the isocenter, the difference was less than 1.5% for all the patients. For independent absorbed-dose calculations, the agreement was also extremely good. For the mean dose for the PTV in particular, the agreement was within 2.0% in all the patients; specifically, no large difference was observed for high-dose regions. Conversely, a significant difference was observed in the mean dose for the OAR. For patients with prostate cancer, the mean rectal dose calculated in Monaco was significantly smaller than that calculated in Pinnacle.

conclusionsThere was no remarkable difference between the SC and XVMC calculations in the high-dose regions. The difference observed in the low-dose regions may have arisen from various causes such as the intrinsic dose deviation in the MC calculation, modeling accuracy, and CT-to-density table used in each planning system It is useful to perform independent absorbed-dose calculations with the MC algorithm in intensity-modulated radiation therapy commissioning.

Indexed as

AlgorithmsMonte Carlo MethodHead and Neck NeoplasmsHumansIntestinal NeoplasmsLung NeoplasmsMalePhantoms, ImagingProstatic NeoplasmsRadiometryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedRetrospective StudiesValidation Studies as Topic

Identifiers

PMID24625221
PMCPMC3995553
OpenAlexW2169898253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.