Evidence map›Paper›PMID 24625044›Full record

Trial reportExperimental aging research2014

Do older adults use the method of loci? Results from the ACTIVE study.

Alden L Gross, Jason Brandt, Karen Bandeen-Roche, Michelle C Carlson, Elizabeth A Stuart, Michael Marsiske, George W Rebok

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Experimental aging research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Comparing Web-Based and Classroom-Based Memory Training for Older Adults: The ACTIVE Memory Works™ Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2020
    Trial
  3. Article
  4. Brain organization of a memory champion.bioRxiv : the preprint server for biology · 2026
    Article
  5. Longitudinal associations of life space mobility and domain-specific cognitive measures in ACTIVE.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Memory rehabilitation during the COVID-19 pandemic.BMC medical informatics and decision making · 2023
    Article
  10. Article
  11. Cognitive Training Effect and Imaging Evidence.Advances in experimental medicine and biology · 2023
    Article
  12. Article
  13. Ancient Mnemonic in New Format-Episodic Memory Training With the Method of Loci in a Smart Phone Application.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alden L Grossa Department of Mental Health , Johns Hopkins Bloomberg School of Public Health , Baltimore , Maryland , USA.
Jason Brandt
Karen Bandeen-Roche
Michelle C Carlson
Elizabeth A Stuart
Michael Marsiske
George W Rebok

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
Translational Researchin Aging Trainnig ProgramT32AG023480 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI LIPSITZ, LEWIS · 2004 to 2024
$7.6M
TRIAL OF A COGNITIVE INTERVENTION FOR OLDER ADULTSU01AG014260 · NIA · JOHNS HOPKINS UNIVERSITY · PI REBOK, GEORGE W. · 1996 to 2010
$3.4M
COGNITIVE APPROACH TO MAINTAINING SELF CARE INVOLVEMENTU01NR004507 · NINR · HEBREW REHABILITATION CENTER FOR AGED · PI MORRIS, JOHN N. · 1996 to 2010
$3.1M
TRIAL OF A COGNITIVE INTERVENTION FOR OLDER ADULTS--CCU01AG014282 · NIA · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI TENNSTEDT, SHARON L · 1996 to 2010
$3.0M
MAINTENANCE AND ENHANCEMENT OF COGNITIVE ADLSU01NR004508 · NINR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI UNVERZAGT, FREDERICK W. · 1996 to 2010
$2.8M
FLUID REASONING TRAINING FOR URBAN ELDERSU01AG014276 · NIA · WAYNE STATE UNIVERSITY · PI MARSISKE, MICHAEL · 1996 to 2010
$2.7M
FLUID ABILITY TRAINING AMONG ELDERLYU01AG014263 · NIA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI WILLIS, SHERRY L · 1996 to 2010
$2.3M
COGNITIVE TRAINING &EVERYDAY COMPETENCE IN THE ELDERLYU01AG014289 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BALL, KARLENE K · 1996 to 2010
$2.3M
NIA NIH HHS P30 AG028740NIA NIH HHS T32 AG023480NIA NIH HHS T32AG023480-07NIA NIH HHS U01 AG014260NIA NIH HHS U01 AG014263NIA NIH HHS U01 AG014276NIA NIH HHS U01 AG014282NIA NIH HHS U01 AG014289NIA NIH HHS U01AG14260NIA NIH HHS U01AG14263NIA NIH HHS U01AG14276NIA NIH HHS U01AG14282NIA NIH HHS U01 AG14289NINR NIH HHS U01 NR004507NINR NIH HHS U01 NR004508NINR NIH HHS U01NR04507NINR NIH HHS U01NR04508
6 · The paper itself

Abstract

unlabelledBACKGROUND/STUDY CONTEXT: The method of loci (MoL) is a complex visuospatial mnemonic strategy. Previous research suggests that older adults could potentially benefit from using the MoL, but that it is too attentionally demanding for them to use in practice. The authors evaluated the hypotheses that training can increase the use of MoL, and that MoL use is associated with better memory.

methodsThe authors analyzed skip patterns on response forms for the Auditory Verbal Learning Test (AVLT) in the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE; N = 1401) trial using 5 years of longitudinal follow-up.

resultsAt baseline, 2% of participants skipped spaces. Fewer than 2% of control participants skipped spaces at any visit across 5 years, but 25% of memory-trained participants, taught the MoL, did so. Participants who skipped spaces used more serial clustering, a hallmark of the MoL (p < .001). Trained participants who skipped spaces showed greater memory improvement after training than memory-trained participants who did not skip spaces (Cohen's d = .84, p = .007), and did not differ in the subsequent rate of long-term memory decline through up to 5 years of follow-up.

conclusionDespite being attentionally demanding, this study suggests that after training, the MoL is used by up to 25% of older adults, and that its use is associated with immediate memory improvement that was sustained through the course of follow-up. Findings are consistent with the notion that older adults balance complexity with novelty in strategy selection, and that changes in strategies used following memory training result in observable qualitative and quantitative differences in memory performance.

Indexed as

LearningAgedAged, 80 and overAgingFemaleHumansMaleMental RecallNeuropsychological TestsVerbal Learning

Identifiers

PMID24625044
PMCPMC3955885

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.