Evidence map›Paper›PMID 24624366›Full record

ArticleFrontiers in cellular and infection microbiology2014

What's in a word: the use, misuse, and abuse of the word "persistence" in Chlamydia biology.

Patrik M Bavoil

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Infection and immunity · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Beta lactamase-producingCurrent research in microbial sciences · 2023
    Article
  7. Occurrence ofPathogens (Basel, Switzerland) · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Characterization of theInfection and immunity · 2018
    Article
  16. Article
  17. Does Active Oral Sex Contribute to Female Infertility?The Journal of infectious diseases · 2017
    Article
  18. Chlamydia trachomatis: the Persistent Pathogen.Clinical and vaccine immunology : CVI · 2017
    Review
  19. Productive and Penicillin-StressedFrontiers in cellular and infection microbiology · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Patrik M BavoilDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland Baltimore, MD, USA.

Funding

Serologic Biomarkers of Human Sexually Transmitted Infection and DiseaseU19AI084044 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KO, DENNIS CHUN-YONE · 2009 to 2018
$22.8M
NIAID NIH HHS U19 AI084044NIAID NIH HHS U19AI084044
6 · The paper itself

Abstract

The word persistence was used by Chlamydia researchers almost as soon as Chlamydia research was born to reflect the propensity of chlamydiae to cause inapparent infection in their hosts, from birds to humans. More recently, the term persistence has been used, misused, and sometimes abused amidst in vitro and in vivo studies that aim to mimick the ability of chlamydiae to emerge from the presumed inapparent state into clinically detectable infection and disease. Here, I have attempted to provide a global perspective on the state of research on chlamydial persistence, revisiting old observations that may warrant a new look, critically evaluating more recent observations and their shortcomings, and including recent developments that may help redefine chlamydiae as pathogens-or not-of both animals and humans.

Indexed as

AnimalsBirdsCarrier StateChlamydiaChlamydia InfectionsChronic DiseaseHumansTerminology as Topicaberrant bodyChlamydiacommensalismpersistencerecurrence

Identifiers

PMID24624366
PMCPMC3940941

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.