ArticleAnnals of laboratory medicine2014
Mean platelet volume and vitamin D level.
Article in Annals of laboratory medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 73 citations in OpenAlex.
- Trial
- Association of Serum Vitamin D Level and Hematological Inflammatory Indices in Participants of the MASHAD Study.Health science reports · 2026Article
- Comparative Study on the Effect of Vitamin D Deficiency on Platelet Indices in COVID-19 and Hepatitis C Patients; an Observational Comparative Study.Health science reports · 2026Article
- Relationship Between Vitamin D Supplementation and Platelet Parameters, Platelet Aggregation and Thrombosis in Healthy Adult Male Dogs: A Pilot Study.Veterinary medicine and science · 2025Article
- Association of Vitamin D Status with Immune Markers in a Cohort of Healthy Adults.The Journal of nutrition · 2025Article
- Vitamin D levels and platelet status in healthy children and adolescent.Frontiers in nutrition · 2025Article
- Vitamin D and cardiovascular diseases: A narrative review.Journal of family medicine and primary care · 2024Review
- The effect of vitamin D deficiency on platelet parameters in patients with COVID-19.Frontiers in cellular and infection microbiology · 2024Article
- Mechanisms Suggesting a Relationship between Vitamin D and Erectile Dysfunction: An Overview.Biomolecules · 2023Review
- 25-Hydroxy Vitamin D Level and Its Correlation with Mean Platelet Volume in Preeclampsia.Iranian journal of public health · 2022Article
- Vitamin D Level in Patients with Consecutive Acute Coronary Syndrome Is Not Correlated with the Parameters of Platelet Activity.Journal of clinical medicine · 2022Article
- Association Between Promoter Methylation of Vitamin D Metabolic Pathway Genes and Tuberculosis and Diabetes Comorbidity in a Chinese Han Population: A Case-Control Study.Journal of inflammation research · 2022Article
- Association of 25-hydroxyvitamin D with hematological profile and anthropometry in patients with glioma.Revista da Associacao Medica Brasileira (1992) · 2022Article
- The Association of 25-Hydroxy Vitamin D level with Mean Platelet Volume in Patients with Acute Coronary Syndrome.Cardiovascular & hematological disorders drug targets · 2022Article
- The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study.ESC heart failure · 2021Article
- Article
- Serum Gamma Glutamyltransferase Is Associated with 25-Hydroxyvitamin D Status in Elderly Patients with Stable Coronary Artery Disease.International journal of environmental research and public health · 2020Article
- Cardiovascular Risk Factors and Haematological Indexes of Inflammation in Paralympic Athletes with Different Motor Impairments.Oxidative medicine and cellular longevity · 2019Article
- Article
- Mean platelet volume is associated with serum 25-hydroxyvitamin D concentrations in patients with stable coronary artery disease.Heart and vessels · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin D deficiency and a high mean platelet volume (MPV) are related to cardiovascular disease. We investigated whether vitamin D deficiency is associated with high MPV.
methodsThis study included 434 patients without chronic disease who were not taking vitamin D or calcium supplements. Vitamin D was measured by chemiluminescent microparticle immunoassay on the Architect-I2000 system (Abbott Diagnostics, USA), and MPV was measured on the Cell-Dyn Ruby analyzer (Abbott Diagnostics). Patients were divided into Groups 1 (138 [men/women, 46/92]), 2 (148 [men/women, 54/94]), and 3 (148 [men/women, 50/98]) according to vitamin D levels of <10 ng/mL, 10-20 ng/mL, and >20 ng/mL, respectively.
resultsThe vitamin D level in Group 1 (7.7±1.9 ng/mL) was lower than that in Group 2 (15.1±1.6 ng/mL, P<0.001) and Group 3 (25.6±6.3 ng/mL, P<0.001). The MPV in Group 3 (7.5±1.0 fL) was lower than that in Group 1 (8.1±1.1 fL, P<0.001) and Group 2 (7.9±1.0 fL, P=0.009). Linear regression analysis showed that low levels of vitamin D (β=-0.109, P=0.019) was independently associated with increased MPV.
conclusionsThere was a strong association between a low vitamin D level and a high MPV; therefore, vitamin D deficiency may be associated with increased MPV.
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