Evidence map›Paper›PMID 24624285›Full record

ReviewJournal of thoracic disease2014

Nontuberculous mycobacterial pulmonary infections.

Margaret M Johnson, John A Odell

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Journal of thoracic disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04463134 (A Prospective Observational Study of Parameters Related to the Clinical Outcomes of NTM Pulmonary Disease in Prince of Wales Hospital), which is not on this map. Cited by 240 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
240citing papers in PubMed, 3 pooled it
25.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04463134 unknown statusnot on this mapstarted 2020, after this paper: background citation

A Prospective Observational Study of Parameters Related to the Clinical Outcomes of NTM Pulmonary Disease in Prince of Wales Hospital

TypeobservationalSponsorChinese University of Hong KongRan2020 to 2023Enrolled50ConditionsClinical OutcomesArmsNTM drug treatment
3 · Its place in the literature

Who cites it

240 citing papers in PubMed, 3 syntheses or guidelines pooled it, 415 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Amikacin Liposome Inhalation Suspension forAnnals of the American Thoracic Society · 2021
    Trial
  6. Trial
  7. Article
  8. Article
  9. Current Perspectives onInternational journal of molecular sciences · 2026
    Review
  10. Pulmonary tuberculosis and the surgeon.Lung India : official organ of Indian Chest Society · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Understanding recurrence inJournal of clinical microbiology · 2026
    Review
  17. Review
  18. Article
  19. Description and complete genome sequence ofFrontiers in microbiology · 2026
    Article
  20. Article

180 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Margaret M Johnson1 Division of Pulmonary Medicine, 2 Department of Cardiothoracic Surgery, Mayo Clinic, Florida, USA.
John A Odell1 Division of Pulmonary Medicine, 2 Department of Cardiothoracic Surgery, Mayo Clinic, Florida, USA.
Mayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary infections due to nontuberculous mycobacteria (NTM) are increasingly recognized worldwide. Although over 150 different species of NTM have been described, pulmonary infections are most commonly due to Mycobacterium avium complex (MAC), Mycobacterium kansasii, and Mycobacterium abscessus. The identification of these organisms in pulmonary specimens does not always equate with active infection; supportive radiographic and clinical findings are needed to establish the diagnosis. It is difficult to eradicate NTM infections. A prolonged course of therapy with a combination of drugs is required. Unfortunately, recurrent infection with new strains of mycobacteria or a relapse of infection caused by the original organism is not uncommon. Surgical resection is appropriate in selected cases of localized disease or in cases in which the infecting organism is resistant to medical therapy. Additionally, surgery may be required for infections complicated by hemoptysis or abscess formation. This review will summarize the practical aspects of the diagnosis and management of NTM thoracic infections, with emphasis on the indications for surgery and the results of surgical intervention. The management of NTM disease in patients with human immunodeficiency virus (HIV) infections is beyond the scope of this article and, unless otherwise noted, comments apply to hosts without HIV infection.

Indexed as

bronchiectasishot tub lungmycobacterium abscessusmycobacterium avium intracellulare (MAI)Nontuberculous mycobacterium (NTM)

Identifiers

PMID24624285
PMCPMC3949190
OpenAlexW1960952604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.