Evidence map›Paper›PMID 24624206›Full record

ArticleJundishapur journal of natural pharmaceutical products2013

In vitro Analysis of Antioxidant, Antimicrobial and Antiproliferative Activity of Enteromorpha antenna, Enteromorpha linza and Gracilaria corticata Extracts.

Manoj Kumar Narasimhan, Shenoy K Pavithra, Vishnupriya Krishnan, Muthukumaran Chandrasekaran

Open access · hybridAbstract read
In one paragraph

Article in Jundishapur journal of natural pharmaceutical products, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 66 citations in OpenAlex.

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  5. Review
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  9. Article
  10. Antimicrobial and Anti-Quorum Sensing Activities of Phlorotannins From Seaweed (Frontiers in cellular and infection microbiology · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Manoj Kumar NarasimhanDepartment of Genetic Engineering, School of Bio-engineering, SRM University, Kattankulathur, India.
Shenoy K PavithraDepartment of Genetic Engineering, School of Bio-engineering, SRM University, Kattankulathur, India.
Vishnupriya KrishnanDepartment of Genetic Engineering, School of Bio-engineering, SRM University, Kattankulathur, India.
Muthukumaran ChandrasekaranDepartment of Industrial Biotechnology, Government College of Technology, Coimbatore, India.
SRM Institute of Science and Technology · INSRM University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeaweeds are taxonomically diverse benthic algae, which are rich in bioactive compounds. These compounds have a potential application in medicine.

objectivesThe aim of the study was to investigate the bioactive properties of three seaweed samples, Enteromorpha antenna, Enteromorpha linza and Gracilaria corticata were collected from the shoreline of Mahabalipuram, Tamilnadu. MATERIALS AND

methodsBioactive components were extracted by using various solvents. Antioxidant analysis methods like scavenging activity of nitric oxide, hydrogen peroxide, hydroxyl radicals, free radical scavenging (DPPH), FRAP (ferric reducing ability plasma) ability and reducing power were carried out. MTT assay was employed to study the anticancer activity against cancer cell lines Hep-G2, MCF7 and normal VERO cell lines.

resultsIt was found that methanolic extracts elicited higher total phenolic content, higher percentage scavenging activity of nitric oxide, hydrogen peroxide, hydroxyl radicals, free radical scavenging (DPPH), FRAP (ferric reducing ability plasma) ability and reducing power. Different concentrations of crude methanolic extracts of seaweeds showed potential antimicrobial activity by well diffusion method. Crude methanolic extract of G. corticata had significant anticancer activity followed by E. antenna and E. linza on cancer cell lines Hep-G2, MCF7 and normal VERO cell lines by MTT assay.

conclusionsThe methanolic extracts of seaweeds Enteromorpha antenna, Enteromorpha linza and Gracilaria corticata possess high total phenolic content and shows a good free radical scavenging activity and hence are proven to have better antioxidant activity and they might be good candidates for further investigations in order to develop potential anticancer drugs.

Indexed as

AntioxidantsReactive Oxygen SpeciesSeaweed

Identifiers

PMID24624206
PMCPMC3941891
OpenAlexW2124373023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.