ReviewJundishapur journal of natural pharmaceutical products2013
Evidence for Clinical Use of Honey in Wound Healing as an Anti-bacterial, Anti-inflammatory Anti-oxidant and Anti-viral Agent: A Review.
Review in Jundishapur journal of natural pharmaceutical products, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 68 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Topical Application of Manuka Honey on Healing After Extraction of Impacted Lower Third Molars: A Split-Mouth Design Randomized Controlled Trial
Comparison of Honey and Povidone-iodine in Wound Healing on Acute Laceration Wounds: A Randomized Controlled Trial Study
Who cites it
68 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Augmentation of the Female Reproductive System Using Honey: A Mini Systematic Review.Molecules (Basel, Switzerland) · 2021Pooled it
- Methanolic extract of Ephedra ciliata promotes wound healing and arrests inflammatory cascade in vivo through downregulation of TNF-α.Inflammopharmacology · 2020Pooled it
- The effect of honey on post-tonsillectomy pain relief: a randomized clinical trial.Brazilian journal of otorhinolaryngologyTrial
- Combination of Manuka Honey and Chitosan-Based Biomaterial for the Treatment of Dehisced Wound: Case Report.Life (Basel, Switzerland) · 2026Article
- Research Progress and Applications of Hydrophilic/Hydrophobic Composites for Antibacterial Hemostatic Dressings.Advanced biology · 2026Review
- Manuka honey as a natural remedy for diabetic foot ulcers: efficacy compared with silver-based dressing.Frontiers in pharmacology · 2026Article
- Comparative Evaluation of Cameroonian Honey and Normal Saline in the Management of Chronic Wounds: A Randomized Controlled Trial.Health science reports · 2026Article
- Recent advancement in molecular pathways and receptor targeting using natural products for wound healing activity.Inflammopharmacology · 2025Review
- The Elimination Effect of Medical-Grade Honey onJournal of clinical medicine research · 2025Article
- Macroscopic Evaluation of Poly(3-hydroxybutyrate-co-3-hydroxy valerate), PHBV-Based Nanofiber Scaffolds with Aloe Vera or Honey in Murine Wound Healing.Pharmaceutics · 2025Article
- The In Vitro Antioxidant and Immunomodulatory Effects of the Irish Monofloral Ivy and Heather Honey Varieties.International journal of molecular sciences · 2025Article
- Three-dimensional bio-derived materials for biomedical applications: challenges and opportunities.RSC advances · 2025Review
- Honey as a Natural Antimicrobial.Antibiotics (Basel, Switzerland) · 2025Review
- Molecular Modification of Queen Bee Acid and 10-Hydroxydecanoic Acid with Specific Tripeptides: Rational Design, Organic Synthesis, and Assessment for Prohealing and Antimicrobial Hydrogel Properties.Molecules (Basel, Switzerland) · 2025Article
- Topical Application of Manuka Honey for the Treatment of Non-Healing Venous Leg Ulcers.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Unlocking the Healing Potential: A Comprehensive Review of Ecology and Biology of Medical-Grade Honey in Wound Management and Tissue Regeneration.Health science reports · 2025Article
- Regulatory role of microRNAs in virus-mediated inflammation.Journal of inflammation (London, England) · 2024Review
- Antibacterial Effect of Spanish Honeys of Different Botanical Origins againstInternational journal of molecular sciences · 2024Article
- Article
- Resolution of necrotizing cellulitis in a dog using basic wound management.The Canadian veterinary journal = La revue veterinaire canadienne · 2024Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextTo provide an updated review of published literature on the anti-oxidant, anti-bacterial and anti-inflammatory properties of honey. EVIDENCE ACQUISITION: CINAHL, BioMed Central, Cochrane Library, Medline and Embase data bases and reference lists were used to find randomized controlled trials and review articles. Randomized controlled trials using honey with a comparator were reviewed, along with published review articles to determine the relative benefits of tropical honey. These methods were undertaken by three reviewers.
resultsHoney has anti-oxidant, anti-bacterial and anti-inflammatory properties. It can be used as a wound dressing to promote rapid and improved healing. These effects are due to honey's anti-bacterial action, secondary to its high acidity, osmotic effect, anti-oxidant content and hydrogen peroxide content. The use of honey leads to improved wound healing in acute cases, pain relief in burn patients and decreased inflammatory response in such patients. However, it has proven to be ineffective in chronic leg ulcers. Overall, studies have been done in favor of the use of honey in medicine.
conclusionsHoney has almost equal or slightly superior effects when compared with conventional treatments for acute wounds and superficial partial thickness burns. More randomized controlled trials with significant statistical power comparing different kinds of honey, are required in order to create a strong body of evidence towards definite recommendations for medical use. There is biological plausibility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.