Evidence map›Paper›PMID 24624135›Full record

ReviewFrontiers in genetics2014

Molecular mechanisms of long ncRNAs in neurological disorders.

Dubravka Vučićević, Heinrich Schrewe, Ulf A Orom

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

  1. Tuning epigenetics to enhance cancer virotherapy.Acta pharmaceutica Sinica. B · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Altered ANRIL Methylation in Epileptic Patients.Journal of molecular neuroscience : MN · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Computational Methods for Identifying Similar Diseases.Molecular therapy. Nucleic acids · 2019
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Editorial focus: entering into the non-coding RNA era.Cellular & molecular biology letters · 2018
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Dubravka VučićevićOtto Warburg Laboratory, Max Planck Institute for Molecular Genetics Berlin, Germany.
Heinrich SchreweDepartment of Developmental Genetics, Max Planck Institute for Molecular Genetics Berlin, Germany.
Ulf A OromOtto Warburg Laboratory, Max Planck Institute for Molecular Genetics Berlin, Germany.
Max Planck Society · DEMax Planck Institute for Molecular Genetics · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (ncRNAs) have added an unexpected layer of complexity in the regulation of gene expression. Mounting evidence now links long ncRNAs to fundamental biological processes such as development and differentiation, and recent research shows important involvement of long ncRNAs in a variety of diseases including neurodegenerative disorders, such as Parkinson's, Alzheimer's, spinocerebellar ataxia, and Huntington's diseases. Furthermore, long ncRNAs are speculated to be implicated in development of psychiatric disorders such as schizophrenia and bipolar disorders. Long ncRNAs contribute to these disorders in diverse ways, from regulation of transcription to modulation of RNA processing and translation. In this review, we describe the diverse mechanisms reported for long ncRNAs, and discuss how they could mechanistically be involved in the development of neurological disorders.

Indexed as

brain developmentlong non-coding RNAncRNAneurological disordersprotein-RNA interaction

Identifiers

PMID24624135
PMCPMC3941653
OpenAlexW2020119496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.