ArticleFrontiers in microbiology2014
High frequency of phylogenetically diverse reductive dehalogenase-homologous genes in deep subseafloor sedimentary metagenomes.
Article in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 67 citations in OpenAlex.
- Evidence of microbial reductive dehalogenation in deep-sea cold seeps and its implications for biogeochemical cycles.Microbiome · 2025Article
- Exploring Microbiological Dynamics in a Salt Cavern for Potential Hydrogen Storage Use.Environmental microbiology reports · 2025Article
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- Exploring the abundance, metabolic potential and gene expression of subseafloor Chloroflexi in million-year-old oxic and anoxic abyssal clay.FEMS microbiology ecology · 2020Article
- Weak Influence of Paleoenvironmental Conditions on the Subsurface Biosphere of Lake Ohrid over the Last 515 ka.Microorganisms · 2020Article
- Mainly on the Plane: Deep Subsurface Bacterial Proteins Bind and Alter Clathrate Structure.Crystal growth & design · 2020Article
- Roles of Organohalide-RespiringmSystems · 2020Article
- Metabolic potential of uncultured bacteria and archaea associated with petroleum seepage in deep-sea sediments.Nature communications · 2019Article
- Presence, Diversity, and Enrichment of Respiratory Reductive Dehalogenase and Non-respiratory Hydrolytic and Oxidative Dehalogenase Genes in Terrestrial Environments.Frontiers in microbiology · 2019Article
- Changes in Carbon Oxidation State of Metagenomes Along Geochemical Redox Gradients.Frontiers in microbiology · 2019Article
- Article
- Ecology and evolution of seafloor and subseafloor microbial communities.Nature reviews. Microbiology · 2018Review
- Deciphering viral presences: two novel partial giant viruses detected in marine metagenome and in a mine drainage metagenome.Virology journal · 2018Article
- Microbial Synthesis and Transformation of Inorganic and Organic Chlorine Compounds.Frontiers in microbiology · 2018Review
- Single-Cell Genomics Reveals a Diverse Metabolic Potential of UncultivatedFrontiers in microbiology · 2018Article
- Climate oscillations reflected within the microbiome of Arabian Sea sediments.Scientific reports · 2017Article
- Are There Rab GTPases in Archaea?Molecular biology and evolution · 2016Article
- Comparative Single-Cell Genomics of Chloroflexi from the Okinawa Trough Deep-Subsurface Biosphere.Applied and environmental microbiology · 2016Article
- Article
- Novel Rhizosphere Soil Alleles for the Enzyme 1-Aminocyclopropane-1-Carboxylate Deaminase Queried for Function with an In Vivo Competition Assay.Applied and environmental microbiology · 2016Article
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14 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marine subsurface sediments on the Pacific margin harbor diverse microbial communities even at depths of several hundreds meters below the seafloor (mbsf) or more. Previous PCR-based molecular analysis showed the presence of diverse reductive dehalogenase gene (rdhA) homologs in marine subsurface sediment, suggesting that anaerobic respiration of organohalides is one of the possible energy-yielding pathways in the organic-rich sedimentary habitat. However, primer-independent molecular characterization of rdhA has remained to be demonstrated. Here, we studied the diversity and frequency of rdhA homologs by metagenomic analysis of five different depth horizons (0.8, 5.1, 18.6, 48.5, and 107.0 mbsf) at Site C9001 off the Shimokita Peninsula of Japan. From all metagenomic pools, remarkably diverse rdhA-homologous sequences, some of which are affiliated with novel clusters, were observed with high frequency. As a comparison, we also examined frequency of dissimilatory sulfite reductase genes (dsrAB), key functional genes for microbial sulfate reduction. The dsrAB were also widely observed in the metagenomic pools whereas the frequency of dsrAB genes was generally smaller than that of rdhA-homologous genes. The phylogenetic composition of rdhA-homologous genes was similar among the five depth horizons. Our metagenomic data revealed that subseafloor rdhA homologs are more diverse than previously identified from PCR-based molecular studies. Spatial distribution of similar rdhA homologs across wide depositional ages indicates that the heterotrophic metabolic processes mediated by the genes can be ecologically important, functioning in the organic-rich subseafloor sedimentary biosphere.
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