Evidence map›Paper›PMID 24624117›Full record

ReviewFrontiers in endocrinology2014

Physical Activity and Bone: May the Force be with You.

Jonathan H Tobias, Virginia Gould, Luke Brunton, Kevin Deere, Joern Rittweger, Matthijs Lipperts, Bernd Grimm

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Osteoporosis in older patients with idiopathic normal pressure hydrocephalus.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  4. Article
  5. Article
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  8. Review
  9. Day-to-day physical activity producing low gravitational impacts is associated with faster visual processing speed at age 69: cross-sectional study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2019
    Article
  10. Article
  11. Article
  12. Article
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  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The Case for Vigorous Physical Activity in Youth.American journal of lifestyle medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jonathan H TobiasMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Avon Orthopaedic Centre, Southmead Hospital , Bristol , UK.
Virginia GouldMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Avon Orthopaedic Centre, Southmead Hospital , Bristol , UK.
Luke BruntonMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Avon Orthopaedic Centre, Southmead Hospital , Bristol , UK.
Kevin DeereMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Avon Orthopaedic Centre, Southmead Hospital , Bristol , UK.
Joern RittwegerGerman Aerospace Center, Institute of Aerospace Medicine , Cologne , Germany.
Matthijs LippertsAtrium Medical Centre, AHORSE Foundation , Heerlen , Netherlands.
Bernd GrimmAtrium Medical Centre, AHORSE Foundation , Heerlen , Netherlands.
Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR) · DE

Funding

Medical Research Council MC_PC_15018Medical Research Council MR/K024973/1Wellcome Trust 102215
6 · The paper itself

Abstract

Physical activity (PA) is thought to play an important role in preventing bone loss and osteoporosis in older people. However, the type of activity that is most effective in this regard remains unclear. Objectively measured PA using accelerometers is an accurate method for studying relationships between PA and bone and other outcomes. We recently used this approach in the Avon Longitudinal Study of Parents and Children (ALSPAC) to examine relationships between levels of vertical impacts associated with PA and hip bone mineral density (BMD). Interestingly, vertical impacts >4g, though rare, largely accounted for the relationship between habitual levels of PA and BMD in adolescents. However, in a subsequent pilot study where we used the same method to record PA levels in older people, no >4g impacts were observed. Therefore, to the extent that vertical impacts need to exceed a certain threshold in order to be bone protective, such a threshold is likely to be considerably lower in older people as compared with adolescents. Further studies aimed at identifying such a threshold in older people are planned, to provide a basis for selecting exercise regimes in older people which are most likely to be bone protective.

Indexed as

BMDboneexerciseimpact loadingphysical activity

Identifiers

PMID24624117
PMCPMC3939444
OpenAlexW2124528241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.