Evidence map›Paper›PMID 24623397›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2014

Prognostic value of left ventricular dyssynchrony by myocardial perfusion-gated SPECT in patients with normal and abnormal left ventricular functions.

Nili Zafrir, Roman Nevzorov, Tamir Bental, Boris Strasberg, Ariel Gutstein, Israel Mats, Ran Kornowski, Alejandro Solodky

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Ventricular dyssynchrony late after the Fontan operation is associated with decreased survival.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  5. Left ventricular mechanical dyssynchrony as a target for therapy in patients with left ventricular aneurysm.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. Prognostic value of ventricular mechanical dyssynchrony in patients with left ventricular aneurysm: A comparative study of medical and surgical treatment.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Mechanisms of left ventricular dyssynchrony: A multinational SPECT study of patients with bundle branch block.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. The prognostic value of diastolic and systolic mechanical left ventricular dyssynchrony among patients with coronary artery disease and heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  9. Is myocardial viability related to left ventricular dyssynchrony?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  10. Article
  11. Analysis of ventricular synchrony: A complex puzzle.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  12. Article
  13. Left ventricular mechanical dyssynchrony graduation of myocardial perfusion gated SPECT phase analysis: What next.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  14. Mechanical dyssynchrony according to validated cut-off values using gated SPECT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  15. Article
  16. Left ventricular mechanical dyssynchrony in patients with coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  17. SPECT and PET in ischemic heart failure.Heart failure reviews · 2017
    Review
  18. Article
  19. Assessment of left ventricular mechanical dyssynchrony in coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nili ZafrirNuclear Cardiology Unit, Rabin Medical Center, Beilinson Campus, 49100, Petah Tikva, Israel, zafrirmd@isdn.net.il.
Roman Nevzorov
Tamir Bental
Boris Strasberg
Ariel Gutstein
Israel Mats
Ran Kornowski
Alejandro Solodky
Rabin Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular (LV) dyssynchrony by phase analysis has been studied by myocardial perfusion imaging (MPI)-gated SPECT in patients with LV dysfunction in various clinical settings. We aimed to investigate the routine use of phase analysis with gated SPECT for predicting cardiac outcome.

methodsPatients referred to a tertiary medical center in 2010-2011 prospectively underwent a gated SPECT and phase analysis, and follow-up for cardiac events. The values of clinical variables, MPI, LV function, and LV dyssynchrony in predicting cardiac events were tested by univariate and multivariate analyses.

resultsThe study group included 787 patients (66.5 ± 11 years, 81% men) followed for a mean duration of 18.3 ± 6.2 months. There were 45 (6%) cardiac events defined as composite endpoint; cardiac death occurred in 26 patients, and the rest had new-onset or worsening heart failure and life-threatening arrhythmias. In multivariate analysis, it was shown that NYHA class, diabetes mellitus, and LVEF <50% were the independent predictors for composite endpoint. However, the independent predictors for cardiac mortality were NYHA class (for each increment in class) and phase standard deviation (SD) (for each 10° increment).

conclusionGated SPECT with phase analysis for the assessment of LV dyssynchrony can successfully predict cardiac death together with NYHA class, in patients with LV dysfunction.

Indexed as

AgedArrhythmias, CardiacCardiac-Gated Single-Photon Emission Computer-Assisted TomographyCausalityComorbidityDeath, Sudden, CardiacFemaleHeart FailureHumansIncidenceIsraelMaleMyocardial Perfusion ImagingPrognosisReference ValuesReproducibility of Results

Identifiers

PMID24623397
OpenAlexW2066356851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.