SynthesisTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2014
Risk of malignancy in focal thyroid lesions identified by (18)F-fluorodeoxyglucose positron emission tomography or positron emission tomography/computed tomography: evidence from a large series of studies.
Synthesis in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Thyroid incidentalomas detected onEuropean radiology · 2026Article
- Diagnostic performances of five US risk stratification systems for malignancy in focal [European radiology · 2025Article
- Meta-Analysis on the Prevalence and Significance of Incidental Findings in the Thyroid Gland Using Other PET Radiopharmaceuticals Beyond [Pharmaceuticals (Basel, Switzerland) · 2025Review
- Definitions of Incidental [Diagnostics (Basel, Switzerland) · 2024Review
- Personalized Diagnosis in Differentiated Thyroid Cancers by Molecular and Functional Imaging Biomarkers: Present and Future.Diagnostics (Basel, Switzerland) · 2022Review
- Radiomics Analysis of [Diagnostics (Basel, Switzerland) · 2022Review
- PET/CT in thyroid nodule and differentiated thyroid cancer patients. The evidence-based state of the art.Reviews in endocrine & metabolic disorders · 2019Review
- Systematic reviews of diagnostic tests in endocrinology: an audit of methods, reporting, and performance.Endocrine · 2017Article
- Thyroid incidentalomas on 18FDG-PET/CT: a metabolico-pathological correlation.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2017Article
- Incidence and Significance of Incidental Focal Thyroid Uptake on (18)F-FDG PET Study in a Large Patient Cohort: Retrospective Single-Centre Experience in the United Kingdom.European thyroid journal · 2015Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Focal thyroid incidentaloma identified on (18)F-fluorodeoxyglucose positron emission tomography or positron emission tomography/computed tomography ((18)F-FDG PET or PET/CT) indicates a high risk of thyroid malignancy. A meta-analysis was performed to investigate whether the maximum standardized uptake value (SUVmax) could discriminate between benign and malignant tissues in focal lesions and to explore the cutoff value of SUVmax for the diagnosis of malignancy. A total of 29 studies were involved in this meta-analysis. The results indicated that there was no statistically significant difference in the size of the two benign and malignant groups when measured by ultrasonography (95 % confidence interval (CI), -0.79 to 0.03 min; p=0.07), while a significantly higher focal SUVmax was observed in the malignant group (95 % CI, 0.34 to 1.05; p=0.0001). In conclusion, the findings of this meta-analysis suggest that a higher focal (18)F-FDG SUVmax was associated with a higher risk of thyroid malignancy, especially at a threshold of 3.3 or more.
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