Evidence map›Paper›PMID 24622721›Full record

ArticleThe lancet. Diabetes & endocrinology2014

Beyond BMI: the need for new guidelines governing the use of bariatric and metabolic surgery.

David E Cummings, Ricardo V Cohen

Abstract read
In one paragraph

Article in The lancet. Diabetes & endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effectiveness of Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy on Lipid Levels in Type 2 Diabetes: a Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
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  17. Bile acids, gut microbiota and metabolic surgery.Frontiers in endocrinology · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

David E CummingsDiabetes and Obesity Center of Excellence and Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, WA, USA. Electronic address: davidec@u.washington.edu.
Ricardo V CohenThe Center of Excellence in Bariatric and Metabolic Surgery, Oswaldo Cruz Hospital, São Paulo, Brazil.

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Sakeneh Zraika · 1986 to 2026
$41.4M
Longtitudinal Assessment of Bariatric Surgery (LABS)U01DK066568 · NIDDK · UNIVERSITY OF WASHINGTON · PI FLUM, DAVID R · 2003 to 2013
$4.3M
Feasibility, Efficacy, and Mechanisms of Surgical vs Medical Diabetes TreatmentR01DK089528 · NIDDK · UNIVERSITY OF WASHINGTON · PI CUMMINGS, DAVID EUSTACE, FLUM, DAVID R · 2010 to 2012
$1.7M
Meal Initiation and Energy Homeostasis: Role of GhrelinR01DK061516 · NIDDK · UNIVERSITY OF WASHINGTON · PI CUMMINGS, DAVID EUSTACE · 2002 to 2009
$1.6M
NIDDK NIH HHS P30 DK017047NIDDK NIH HHS P30 DK17047NIDDK NIH HHS R01 DK061516NIDDK NIH HHS R01 DK089528NIDDK NIH HHS R01 DK517498NIDDK NIH HHS R01 DK61516NIDDK NIH HHS U01 DK066568NIDDK NIH HHS U01 DK66568
6 · The paper itself

Abstract

Bariatric surgery use is largely governed worldwide by a 1991 National Institutes of Health consensus statement that advocates BMI as the primary operative criterion and restricts surgery to severely obese patients. These guidelines have been enormously valuable in standardising practice, thereby facilitating accumulation of a copious database of information regarding long-term surgical benefits and risks, from vast clinical experience and research. However, the National Institutes of Health recommendations had important limitations from the outset and are now gravely outdated. They do not account for remarkable advances in minimally invasive surgical techniques or the development of entirely new procedures. In the two decades since they were crafted, we have gained far greater understanding of the dramatic, weight-independent benefits of some operations on metabolic diseases, especially type 2 diabetes, and of the inadequacy of BMI as a primary criterion for surgical selection. Furthermore, there is now a substantial and rapidly burgeoning body of level-1 evidence from randomised trials comparing surgical versus non-surgical approaches to obesity, type 2 diabetes, and other metabolic diseases, including among only mildly obese or merely overweight patients. Herein, we present arguments to impel the development of new guidelines for the use of bariatric and so-called metabolic surgery to inform clinical practice and insurance compensation.

Indexed as

Body Mass IndexBariatric SurgeryDiabetes Mellitus, Type 2Guidelines as TopicObesity

Identifiers

PMID24622721
PMCPMC4160116

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.