ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2014
Acute effects of alcohol on stimulus-induced gamma oscillations in human primary visual and motor cortices.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Stress and alcohol impact network states involved in emotional processing: relevance of comorbid AUD and psychiatric illnesses.Psychopharmacology · 2026Pooled it
- The neurobiological markers of acute alcohol's subjective effects in humans.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Trial
- No effects of transcranial direct current stimulation on visual evoked potential and peak gamma frequency.Cognitive processing · 2022Trial
- Naturalizing perceptual experience: the explanatory power of probabilistic computation and the holographic solution.Frontiers in human neuroscience · 2026Article
- Alcohol effects on associative and sensorimotor cortico-thalamo-basal ganglia circuits alter decision making and alcohol intake.Alcohol (Fayetteville, N.Y.) · 2025Review
- Measuring the neurodevelopmental trajectory of excitatory-inhibitory balance via visual gamma oscillations.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Sex-specific Differences in Resting Oscillatory Dynamics in Children with Prenatal Alcohol Exposure.Neuroscience · 2024Article
- The acute effects of psychoactive drugs on emotional episodic memory encoding, consolidation, and retrieval: A comprehensive review.Neuroscience and biobehavioral reviews · 2023Review
- Individual/Peak Gamma Frequency: What Do We Know?Brain sciences · 2023Review
- Extraction of Individual EEG Gamma Frequencies from the Responses to Click-Based Chirp-Modulated Sounds.Sensors (Basel, Switzerland) · 2023Article
- Article
- Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk.Translational psychiatry · 2021Article
- Tiagabine induced modulation of oscillatory connectivity and activity match PET-derived, canonical GABA-A receptor distributions.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2021Article
- Visual gamma oscillations predict sensory sensitivity in females as they do in males.Scientific reports · 2021Article
- Compensatory neuroadaptation to binge drinking: Human evidence for allostasis.Addiction biology · 2021Article
- Response certainty during bimanual movements reduces gamma oscillations in primary motor cortex.NeuroImage · 2021Article
- Moderate Alcohol Intake Changes Visual Perception by Enhancing V1 Inhibitory Surround Interactions.Frontiers in neuroscience · 2021Article
- The Role of Gamma Oscillations in the Pathophysiology of Substance Use Disorders.Journal of personalized medicine · 2020Review
- Generative modelling of the thalamo-cortical circuit mechanisms underlying the neurophysiological effects of ketamine.NeuroImage · 2020Article
- Region-dependent regulation of acute ethanol on γ oscillation in the rat hippocampal slices.Psychopharmacology · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Alcohol is a rich drug affecting both the γ-amino butyric acid (GABA) and glutamatergic neurotransmitter systems. Recent findings from both modeling and pharmacological manipulation have indicated a link between GABAergic activity and oscillations measured in the gamma frequency range (30-80 Hz), but there are no previous reports of alcohol's modulation of gamma-band activity measured by magnetoencephalography (MEG) or electroencephalography (EEG). In this single-blind, placebo-controlled crossover study, 16 participants completed two study days, on one day of which they consumed a dose of 0.8 g/kg alcohol, and on the other day a placebo. MEG recordings of brain activity were taken before and after beverage consumption, using visual grating and finger abduction paradigms known to induce gamma-band activity in the visual and motor cortices respectively. Time-frequency analyses of beamformer source reconstructions in the visual cortex showed that alcohol increased peak gamma amplitude and decreased peak frequency. For the motor task, alcohol increased gamma amplitude in the motor cortex. These data support the notion that gamma oscillations are dependent, in part, on the balance between excitation and inhibition. Disruption of this balance by alcohol, by increasing GABAergic inhibition at GABAA receptors and decreasing glutamatergic excitation at N-methyl-D-aspartic acid receptors, alters both the amplitude and frequency of gamma oscillations. The findings provide further insight into the neuropharmacological action of alcohol.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.