ReviewDevelopment and psychopathology2014
Contributions of magnetic resonance spectroscopy to understanding development: potential applications in the study of adolescent alcohol use and abuse.
Review in Development and psychopathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Trial
- Multi-modal neuroimaging reveals differences in alcohol-cue reactivity but not neurometabolite concentrations in adolescents who drink alcohol.Drug and alcohol dependence · 2024Article
- The cross-sectional interplay between neurochemical profile and brain connectivity.Human brain mapping · 2021Article
- Alcohol Consumption among Freshman College Students in Spain: Individual and Pooled Analyses of Three Cross-Sectional Surveys (2005, 2012 and 2016).International journal of environmental research and public health · 2021Article
- An investigation of the relationship between glutamate and resting state connectivity in chronic cannabis users.Brain imaging and behavior · 2020Article
- Effect of alcohol use on the adolescent brain and behavior.Pharmacology, biochemistry, and behavior · 2020Review
- Neonatal brain metabolite concentrations: Associations with age, sex, and developmental outcomes.PloS one · 2020Article
- An Investigation of Neurochemical Changes in Chronic Cannabis Users.Frontiers in human neuroscience · 2019Article
- Miniature pig magnetic resonance spectroscopy model of normal adolescent brain development.Journal of neuroscience methods · 2018Article
- Neurobiological signatures associated with alcohol and drug use in the human adolescent brain.Neuroscience and biobehavioral reviews · 2016Review
- Impact of family history of alcoholism on glutamine/glutamate ratio in anterior cingulate cortex in substance-naïve adolescents.Developmental cognitive neuroscience · 2015Article
- GABAergic contributions to alcohol responsivity during adolescence: insights from preclinical and clinical studies.Pharmacology & therapeutics · 2014Review
- A Review of Magnetic Resonance Spectroscopy Studies in Marijuana using Adolescents and Adults.Journal of addiction research & therapy · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
A growing body of research has documented structural and functional brain development during adolescence, yet little is known about neurochemical changes that occur during this important developmental period. Magnetic resonance spectroscopy (MRS) is a well-developed technology that permits the in vivo quantification of multiple brain neurochemicals relevant to neuronal health and functioning. However, MRS technology has been underused in exploring normative developmental changes during adolescence and the onset of alcohol and drug use and abuse during this developmental period. This review begins with a brief overview of normative cognitive and neurobiological development during adolescence, followed by an introduction to MRS principles. The subsequent sections provide a comprehensive review of the existing MRS studies of development and cognitive functioning in healthy children and adolescents. The final sections of this article address the potential application of MRS in identifying neurochemical predictors and consequences of alcohol use and abuse in adolescence. MRS studies of adolescent populations hold promise for advancing our understanding of neurobiological risk factors for psychopathology by identifying the biochemical signatures associated with healthy brain development, as well as neurobiological and cognitive correlates of alcohol and substance use and abuse.
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Registered trials
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