ArticlePloS one2014
Speed and duration of walking and other leisure time physical activity and the risk of heart failure: a prospective cohort study from the Copenhagen City Heart Study.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Leisure-time and occupational physical activity and risk of cardiovascular disease incidence: a systematic-review and dose-response meta-analysis of prospective cohort studies.The international journal of behavioral nutrition and physical activity · 2024Pooled it
- Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies.British journal of sports medicine · 2023Pooled it
- Physical activity and the risk of heart failure: a systematic review and dose-response meta-analysis of prospective studies.European journal of epidemiology · 2021Pooled it
- Outdoor Walking Speeds of Apparently Healthy Adults: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- Physical Activity and Prognosis in the TOPCAT Trial (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist).Circulation · 2017Trial
- The performance of a machine learning model in predicting accelerometer-derived walking speed.Heliyon · 2025Article
- Mendelian randomisation and mediation analysis of self-reported walking pace and coronary artery disease.Scientific reports · 2024Article
- Classification of moderate-intensity overground walking speed in 21- to 85-year-old adults.Journal of sports sciences · 2022Article
- The association of walking pace and incident heart failure and subtypes among postmenopausal women.Journal of the American Geriatrics Society · 2022Article
- Self-Reported Walking Pace and Risk of Cardiovascular Diseases: A Two-Sample Mendelian Randomization Study.Frontiers in genetics · 2022Article
- Complexity-Based Decoding of the Coupling Among Heart Rate Variability (HRV) and Walking Path.Frontiers in physiology · 2020Article
- Association of gait speed and grip strength with risk of cardiovascular events in patients on haemodialysis: a prospective study.BMC nephrology · 2019Observational
- Prospective Association of Physical Activity and Heart Failure Hospitalizations Among Black Adults With Normal Ejection Fraction: The Jackson Heart Study.Journal of the American Heart Association · 2017Observational
- Step-Based Physical Activity Metrics and Cardiometabolic Risk: NHANES 2005-2006.Medicine and science in sports and exercise · 2017Article
- Cellular telephone use during free-living walking significantly reduces average walking speed.BMC research notes · 2016Article
- Measurement properties of the Human Activity Profile questionnaire in hospitalized patients.Brazilian journal of physical therapyArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimPhysical activity (PA) confers some protection against development of heart failure (HF) but little is known of the role of intensity and duration of exercise. METHODS AND
resultsIn a prospective cohort study of men and women free of previous MI, stroke or HF with one or more examinations in 1976-2003, we studied the association between updated self-assessed leisure-time PA, speed and duration of walking and subsequent hospitalization or death from HF. Light and moderate/high level of leisure-time PA and brisk walking were associated with reduced risk of HF in both genders whereas no consistent association with duration of walking was seen. In 18,209 subjects age 20-80 with 1580 cases of HF, using the lowest activity level as reference, the confounder-adjusted hazard ratios (HR) for light and moderate/high leisure-time physical activity were 0.75 (0.66-0.86) and 0.80 (0.69-0.93), respectively. In 9,937 subjects with information on walking available and 542 cases of HF, moderate and high walking speed were associated with adjusted HRs of 0.53 (0.43-0.66) and 0.30 (0.21-0.44), respectively, and daily walking of ½-1 hrs, 1-2 and >2 hrs with HR of 0.80 (0.61-1.06), 0.82 (0.62-1.06), and 0.96 (0.73-1.27), respectively. Results were similar for both genders and remained robust after exclusion of HF related to coronary heart disease and after a series of sensitivity analyses.
conclusionsSpeed rather than duration of walking was associated with reduced risk of HF. Walking is the most wide-spread PA and public health measures to curb the increase in HF may benefit from this information.
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