Evidence map›Paper›PMID 24619761›Full record

ArticleAmerican journal of clinical pathology2014

Placental histomorphometry in gestational diabetes mellitus: the relationship between subsequent type 2 diabetes mellitus and race/ethnicity.

Rhonda Bentley-Lewis, Deanna L Dawson, Julia B Wenger, Ravi I Thadhani, Drucilla J Roberts

Open access · bronzeAbstract read
In one paragraph

Article in American journal of clinical pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Trial
  5. Article
  6. Article
  7. Article
  8. Gestational diabetes mellitus induces placental vasculopathies.Environmental science and pollution research international · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rhonda Bentley-LewisBentley-Lewis.Rhonda@mgh.harvard.edu.
Deanna L Dawson
Julia B Wenger
Ravi I Thadhani
Drucilla J Roberts
Massachusetts General Hospital · US

Funding

Patient Oriented Studies of Vitamin D in Chronic Kidney DiseaseK24DK094872 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI THADHANI, RAVI · 2012 to 2016
$546k
Metabolomic profiling in the prediction of Gestational Diabetes MellitusR03DK096152 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BENTLEY-LEWIS, RHONDA · 2012 to 2014
$475k
NIDDK NIH HHS 1R03DK096152NIDDK NIH HHS K24 DK094872NIDDK NIH HHS R03 DK096152
6 · The paper itself

Abstract

objectivesWe examined placental histomorphometry in gestational diabetes mellitus (GDM) for factors associated with race/ethnicity and subsequent type 2 diabetes mellitus (T2DM).

methodsWe identified 124 placentas from singleton, full-term live births whose mothers had clinically defined GDM and self-reported race/ethnicity. Clinical and placental diagnoses were abstracted from medical records.

resultsForty-eight white and 76 nonwhite women were followed for 4.1 years (median, range 0.0-8.9 years). White women developed less T2DM (12.5% vs 35.5%; P = .005) but had higher systolic (mean ± SD, 116 ± 13 vs 109 ± 11 mm Hg; P < .001) and diastolic (71 ± 9 vs 68 ± 7 mm Hg; P = .02) blood pressure, more smoking (35.4% vs 10.5%; P = .004), and more chorangiosis (52.1% vs 30.3%; P = .02) than nonwhite women.

conclusionsAlthough more nonwhite women developed T2DM, more white women had chorangiosis, possibly secondary to the higher percentage of smokers among them. Further study is necessary to elucidate the relationship among chorangiosis, subsequent maternal T2DM, and race.

Indexed as

AdultAsian PeopleBlack PeopleDiabetes, GestationalDiabetes Mellitus, Type 2FemaleHumansPlacentaPregnancyRisk FactorsSmokingWhite PeopleGestational diabetes mellitusPlacental histomorphometryRace/ethnicityType 2 diabetes mellitus

Identifiers

PMID24619761
PMCPMC4040002
OpenAlexW2246057092

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.