Evidence map›Paper›PMID 24619402›Full record

ArticlePharmaceuticals (Basel, Switzerland)2010

Role of the G Protein-Coupled Receptor, mGlu

Janet Wangari-Talbot, James Goydos, Suzie Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Targeting cancer metabolism.Clinical cancer research : an official journal of the American Association for Cancer Research · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Janet Wangari-TalbotGraduate School of Biomedical Sciences-Robert Wood Johnson Medical School, Piscataway, 08854 New Jersey, USA ; Department of Surgery, Cancer Institute of New Jersey, New Brunswick, 08901 New Jersey, USA ; Susan Lehman Cullman Laboratory for Cancer Research, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, 08854-8020 New Jersey, USA.
James GoydosGraduate School of Biomedical Sciences-Robert Wood Johnson Medical School, Piscataway, 08854 New Jersey, USA ; Department of Surgery, Cancer Institute of New Jersey, New Brunswick, 08901 New Jersey, USA.
Suzie ChenSusan Lehman Cullman Laboratory for Cancer Research, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, 08854-8020 New Jersey, USA.
Cancer Institute of Florida · USRutgers, The State University of New Jersey · US

Funding

Validation of Grm1 as a Therapeutic Target in MelanomaR01CA124975 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI GOYDOS, JAMES S. · 2007 to 2011
$1.9M
SPONTANEOUS MELANOMA DEVELOPMENT IN TRANSGENIC MICER01CA074077 · NCI · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI CHEN, SUZIE · 1998 to 2003
$934k
MSU-UMDNJ-GSBS Bridge to the DoctorateR25GM066338 · NIGMS · MONTCLAIR STATE UNIVERSITY · PI VEGA, QUINN C · 2002 to 2007
$770k
NCI NIH HHS R01 CA074077NCI NIH HHS R01 CA124975NIGMS NIH HHS R25 GM066338
6 · The paper itself

Abstract

Melanoma remains one of the cancers for which a decline in morbidity has not been achieved with current scientific and medical advances. Mono-therapies targeting melanoma have been largely ineffective, increasing the need for identification of new drugable targets. Multiple tumor suppressors and oncogenes that impart genetic predisposition to melanoma have been identified and are being studied in an attempt to provide insight on the development of anti-melanoma therapies. Metabotropic Glutamate Receptor I (

Indexed as

GPCRGRM1MelanomamGlu1

Identifiers

PMID24619402
PMCPMC3947795
OpenAlexW2026949733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.