SynthesisDigestive diseases and sciences2014
Efficacy and safety of endoscopic submucosal dissection for superficial squamous esophageal neoplasia: a meta-analysis.
Synthesis in Digestive diseases and sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Endoscopic resection of early esophageal neoplasia in patients with esophageal varices: a systematic review.Endoscopy · 2025Pooled it
- Efficacy and safety of endoscopic submucosal tunnel dissection for superficial esophageal neoplastic lesions: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2020Pooled it
- Guideline
- Prospective study of endoscopic focal cryoballoon ablation for esophageal squamous cell neoplasia in China.Gastrointestinal endoscopy · 2019Trial
- Hybrid endoscopic submucosal dissection reduces procedure time for superficial esophageal squamous carcinomas ≤ 2 cm: a single-center retrospective propensity score-matched analysis.Surgical endoscopy · 2026Article
- Comparative effectiveness of the Clutch Cutter versus Dual knife for esophageal endoscopic submucosal dissection by non-expert endoscopists: a single-center retrospective cohort study.BMC gastroenterology · 2026Article
- Comparison of the Efficacy and Safety of General Anesthesia and Sedation Management for Esophageal Endoscopic Submucosal Dissection: A Retrospective Study.JMA journal · 2026Article
- Advancements in endoscopic closure: Embracing a new era of managing complications and postprocedural defects after endoscopic submucosal dissection.World journal of gastrointestinal endoscopy · 2025Review
- Comparative study on different endoscopic submucosal dissection techniques for the treatment of superficial esophageal cancer and precancerous lesions.BMC gastroenterology · 2025Article
- Optimal direct oral anticoagulant for upper gastrointestinal endoscopic submucosal dissection.Journal of gastroenterology · 2025Article
- Repeat endoscopic submucosal dissection close to the initial endoscopic submucosal dissection scar for superficial esophageal squamous cell carcinoma.Esophagus : official journal of the Japan Esophageal Society · 2024Article
- Usefulness of an ultrathin endoscope in esophageal endoscopic submucosal dissection.Endoscopy international open · 2024Article
- Endoscopic submucosal dissection for early esophageal squamous cell carcinoma: long-term results from a Western cohort.Endoscopy · 2024Article
- Assessment of delayed bleeding after endoscopic submucosal dissection of early-stage gastrointestinal tumors in patients receiving direct oral anticoagulants.World journal of gastroenterology · 2023Review
- Endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma: long-term follow-up in a Western center.Clinical endoscopy · 2023Article
- Evaluation of long-term survival in patients with severe comorbidities after endoscopic submucosal dissection for esophageal squamous cell carcinoma.Surgical endoscopy · 2022Article
- Outcomes of endoscopic submucosal dissection for superficial esophageal neoplasms in patients with liver cirrhosis.Clinical endoscopy · 2022Article
- Advanced Endoscopic Resection Techniques: Endoscopic Submucosal Dissection and Endoscopic Full-Thickness Resection.Digestive diseases and sciences · 2022Review
- [Treatment recommendations for early esophageal cancer : Endoscopic and surgical options].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- Predictive factors for difficult endoscopic submucosal dissection for esophageal neoplasia including failure of en bloc resection or perforation.Surgical endoscopy · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsAlthough endoscopic submucosal dissection (ESD) has grown popular in resecting lesions in the stomach, the application of ESD to the esophagus has been limited by greater technical difficulty. An increasing number of series have recently reported the application of ESD to esophageal lesions. The aim of the present systemic review and meta-analysis was to evaluate the efficacy and safety of ESD for esophageal lesions.
methodsComprehensive literature searches (1999-2012) were performed on studies that reported ESD for the removal of esophageal neoplasia. Primary outcome measures were pooled estimates of complete resection rate and en bloc resection rate. Secondary outcome measures were pooled estimates of complication rates.
resultsA total of 15 studies provided data on 776 ESD-treated lesions. The pooled estimate of complete resection rate was 89.4% (95% CI 86.2-91.9%). The pooled estimate of en bloc resection was 95.1% (95% CI 92.6-96.8%). The pooled estimates of complications of ESD such as bleeding, perforation, and stenosis were 2.1, 5.0, and 11.6%, respectively.
conclusionsESD appeared to be an extremely effective technique to achieve complete resection of esophageal neoplasia. The very low rate of complications also shows the potential safety of this approach.
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