ArticleCirculation. Cardiovascular imaging2014
Cardiac magnetic resonance parameters predict transplantation-free survival in patients with fontan circulation.
Article in Circulation. Cardiovascular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 58 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 136 citations in OpenAlex.
- SCMR Position Paper (2020) on clinical indications for cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020Guideline
- Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis.Pediatric cardiology · 2020Trial
- Examination of elevated myocardial extracellular volume and exercise capacity in pediatric Fontan patients at moderate altitude.Pediatric radiology · 2026Article
- Computed tomography and magnetic resonance imaging findings in congenital cardiovascular anomalies.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Review
- The Feasibility and Reproducibility of Measuring Myocardial Performance Index Using Two-Dimensional Phase Contrast Imaging in Patients with Congenital Heart Disease.Pediatric cardiology · 2026Article
- Epicardial Fat is Associated with Ventricular Dilation in Patients After the Fontan Operation.Pediatric cardiology · 2026Article
- Beyond volumes and ejection fraction: practical insights into cine-CMR interpretation and applications.The international journal of cardiovascular imaging · 2025Review
- Cardiovascular imaging in children with cardiac implantable electronic devices.Pediatric radiology · 2025Review
- Multimodal Imaging from Fetal to Adult Life: A Comprehensive Approach to Hypoplastic Left Heart Syndrome (HLHS).Journal of cardiovascular development and disease · 2025Review
- Cardiac magnetic resonance imaging assessment of myocardial disease in children and adolescents.Cardiovascular diagnosis and therapy · 2025Review
- Cardiac MRI in patients with Fontan circulation: assessing risk factors for adverse outcomes.Open heart · 2025Article
- Cardiac and Liver Fibrosis Assessed by Multiparametric MRI in Patients with Fontan Circulation.Pediatric cardiology · 2025Article
- Diastolic dysfunction in patients with Fontan palliation is associated with death and heart transplantation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Article
- Impact of cardiovascular magnetic resonance in single ventricle physiology: a narrative review.Cardiovascular diagnosis and therapy · 2024Review
- Right Ventricular Remodeling and Function in Hypoplastic Left Heart Syndrome.JACC. Advances · 2024Review
- Central Venous Waveform Patterns in the Fontan Circulation Independently Contribute to the Prediction of Composite Survival.Pediatric cardiology · 2024Review
- Cardiovascular Computed Tomography and Magnetic Resonance Imaging Guideline of the Brazilian Society of Cardiology and the Brazilian College of Radiology - 2024.Arquivos brasileiros de cardiologia · 2024Article
- High-Performing Fontan Patients: A Fontan Outcome Registry by Cardiac Magnetic Resonance Imaging Study.JACC. Advances · 2024Article
- Application of Principal Component Analysis to Heterogenous Fontan Registry Data Identifies Independent Contributing Factors to Decline.medRxiv : the preprint server for health sciences · 2024Article
- Effects of cardiac growth on electrical dyssynchrony in the single ventricle patient.Computer methods in biomechanics and biomedical engineering · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSeveral clinical risk factors for death and heart transplantation have been identified in patients with Fontan circulation. It is unknown whether cardiac magnetic resonance (CMR) measurements of ventricular size and function are independently associated with these outcomes and further improve risk stratification. METHODS AND
resultsData on patients with Fontan circulation who had a CMR study from January 2002 to January 2011 were retrospectively reviewed. The end point was time to death or listing for heart transplantation after the CMR study. The median age of the 215 patients was 18.3 years (25th, 75th percentiles: 14, 26) with a median age at Fontan of 3.6 years (2.3, 7.1). During a median post-CMR follow-up period of 4.1 years (2.6, 6.2), 24 patients (11%) reached the end point: 20 deaths, 3 transplantations, and 1 transplantation listing. In a multivariable Cox regression model with clinical parameters only, protein-losing enteropathy was associated with death or listing for transplant. A multivariable model, including clinical and CMR parameters, showed that in addition to protein-losing enteropathy, ventricular indexed end-diastolic volume >125 mL/body surface area raised to the 1.3 power was associated with the endpoint. A likelihood-ratio test comparing the 2 models showed that the addition of indexed end-diastolic volume resulted in a significantly improved end point prediction (P<0.001)-C-index increased from 0.63 to 0.79.
conclusionsCMR-derived ventricular indexed end-diastolic volume is an independent predictor of death or transplant in patients late after the Fontan operation and adds incremental value over clinical symptoms alone for risk stratification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.