Evidence map›Paper›PMID 24618998›Full record

ReviewCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2014

Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention.

Parisa Karimi, Farhad Islami, Sharmila Anandasabapathy, Neal D Freedman, Farin Kamangar

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1,054 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,054citing papers in PubMed, 6 pooled it
49.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06576921 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy and Safety of Serplulimab Combined With Nab-paclitaxel and SOX as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorXijing HospitalRan2024 to 2026Enrolled116ConditionsStomach Neoplasms, Immune Checkpoint InhibitorsArmsSerplulimab Combined With Chemotherapy, Placebo combined with Chemotherapy
NCT06707714 enrolling by invitationnot on this mapstarted 2023, after this paper: background citation

A Metabolomics-based Study to Explore the Mechanism of Remission of Metabolic Syndrome After Radical Gastrectomy

Typeobservational_patient_registrySponsorDong PengRan2023 to 2026Enrolled150ConditionsMetabolic Syndrome, Gastric CancerArmshypertension, diabetes, fatty liver
3 · Its place in the literature

Who cites it

1,054 citing papers in PubMed, 6 syntheses or guidelines pooled it, 1,921 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Burden of Gastric Cancer in China from 1990 to 2023.Public health in practice (Oxford, England) · 2026
    Article
  9. Article
  10. Article
  11. FMRP promotes gastric cancer progression via mJournal of translational medicine · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

994 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Parisa KarimiAuthors' Affiliations: Johns Hopkins Bloomberg School of Public Health; Department of Public Health Analysis, School of Community Health and Policy, Morgan State University, Baltimore; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland; Institute for Transitional Epidemiology, Mount Sinai School of Medicine; Division of Gastroenterology, Department of Medicine, Mount Sinai Medical Center, New York, New York; and Digestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Farhad Islami
Sharmila Anandasabapathy
Neal D Freedman
Farin Kamangar
Division of Cancer Epidemiology and GeneticsIcahn School of Medicine at Mount Sinai · US

Funding

Upper Gastrointestinal Cancer StudiesZIACP000185 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ABNET, CHRISTIAN · 2009 to 2025
$25.6M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Less than a century ago, gastric cancer was the most common cancer in the United States and perhaps throughout the world. Despite its worldwide decline in incidence over the past century, gastric cancer remains a major killer across the globe. This article reviews the epidemiology, screening, and prevention of gastric cancer. We first discuss the descriptive epidemiology of gastric cancer, including its incidence, survival, mortality, and trends over time. Next, we characterize the risk factors for gastric cancer, both environmental and genetic. Serologic markers and histological precursor lesions of gastric cancer and early detection of gastric cancer using these markers are reviewed. Finally, we discuss prevention strategies and provide suggestions for further research.

Indexed as

Early Detection of CancerHumansRisk FactorsStomach Neoplasms

Identifiers

PMID24618998
PMCPMC4019373
OpenAlexW2095725724

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.