ArticlePloS one2014
Transcriptome analysis of silkworm, Bombyx mori, during early response to Beauveria bassiana challenges.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 59 citations in OpenAlex.
- Towards a Rational Basis for the Selection of Probiotics to Improve Silkworm Health and Performance.Insects · 2025Review
- Comparative Transcriptomics of the Entomopathogenic Fungus Beauveria bassiana Grown on Aerial Surface and in Liquid Environment.Current microbiology · 2024Article
- The humoral immune response of the lepidopteran model insect, silkwormCurrent research in insect science · 2024Review
- Effects of the Entomopathogenic FungusInsects · 2023Article
- Physiological and transcriptional immune responses of a non-model arthropod to infection with different entomopathogenic groups.PloS one · 2022Article
- An Expanded Survey of the Moth PBP/GOBP Clade inFrontiers in physiology · 2021Article
- Article
- Quality Formation Mechanism of Stiff Silkworm,Molecules (Basel, Switzerland) · 2019Article
- Diet modulates the relationship between immune gene expression and functional immune responses.Insect biochemistry and molecular biology · 2019Article
- Identification of cordycepin biosynthesis-related genes through de novo transcriptome assembly and analysis inRoyal Society open science · 2018Article
- Article
- RNA-Seq Analyses for Two Silkworm Strains Reveals Insight into Their Susceptibility and Resistance to Beauveria bassiana Infection.International journal of molecular sciences · 2017Article
- Molecular Cloning, Bioinformatic Analysis, and Expression ofBioMed research international · 2017Article
- Genome-Wide Host-Pathogen Interaction Unveiled by Transcriptomic Response of Diamondback Moth to Fungal Infection.PloS one · 2016Article
- Genome-Wide Analysis of Host Responses to Four Different Types of Microorganisms in Bombyx Mori (Lepidoptera: Bombycidae).Journal of insect science (Online) · 2016Article
- Comparative Transcriptome Analysis Reveals Different Silk Yields of Two Silkworm Strains.PloS one · 2016Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Host-pathogen interactions are complex processes and it is a central challenge to reveal these interactions. Fungal infection of silkworm, Bombyx mori, may induce a variety of responsive reaction. However, little is known about the molecular mechanism of silkworm immune response against the fungal infection. To obtain an overview of the interaction between silkworm and an entomopathogenic fungus Beauveria bassiana, Digital Gene Expression profiling, a tag based high-throughput transcriptome sequencing method, was employed to screen and identify differentially expressed genes (DEGs, FDR ≤ 0.001, ∣log2ratio∣ ≥ 1) of silkworm larvae during early response against B. bassiana infection. Total 1430 DEGs including 960 up-regulated and 470 down-regulated ones were identified, of which 627 DEGs can be classified into GO categories by Gene Ontology (GO) analysis. KEGG pathways analysis of these DEGs suggested that many biological processes, such as defense and response, signal transduction, phagocytosis, regulation of gene expression, RNA splicing, biosynthesis and metabolism, protein transport etc. were involved in the interaction between the silkworm and B. bassiana. A number of differentially expressed fungal genes were also identified by mapping the sequencing tags to B. bassiana genome. These results provided new insights to the molecular mechanism of silkworm immune response to B. bassiana infection.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.