ArticleFrontiers in microbiology2014
Transcriptome analysis of Listeria monocytogenes exposed to biocide stress reveals a multi-system response involving cell wall synthesis, sugar uptake, and motility.
Article in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 99 citations in OpenAlex.
- Genetic variations and accelerated growth at low temperatures in aMicrobiology spectrum · 2026Article
- Transcriptome Sequencing Reveals Distinct Stress Response of Listeria monocytogenes 6179 During Logarithmic and Stationary Growth Phases.MicrobiologyOpen · 2025Article
- New insights into the stress response mechanisms of stress-resistantEmerging microbes & infections · 2025Article
- Adaptive Tolerance of Listeria monocytogenes to Chemical Oxidants: Comparative Analysis of Transcriptomic Studies.Comprehensive reviews in food science and food safety · 2025Review
- The Virulence Factor LLO ofFoods (Basel, Switzerland) · 2025Article
- Exploring the potential ofFrontiers in microbiology · 2025Article
- Investigating the role of theFEMS microbes · 2025Article
- Impact of the Stress Response on Quaternary Ammonium Compound Disinfectant Susceptibility inMicroorganisms · 2024Article
- Effects of intrinsic and extrinsic growth factors on virulence gene expression of foodborne pathogens in vitro and in food model systems; a review.Food science & nutrition · 2024Review
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- Deciphering the impact of exogenous fatty acids onFrontiers in microbiology · 2024Article
- Biofilms, mobile genetic elements and the persistence of pathogens on environmental surfaces in healthcare and food processing environments.Frontiers in microbiology · 2024Review
- Closed genome sequences of twoMicrobiology resource announcements · 2023Article
- Comparative genomics unveils extensive genomic variation between populations of Listeria species in natural and food-associated environments.ISME communications · 2023Article
- Chlorine Dioxide Reprograms Rhizosphere Microbial Communities to Enrich Interactions with Tobacco (Polish journal of microbiology · 2023Article
- Impact of benzalkonium chloride, benzethonium chloride and chloroxylenol on bacterial antimicrobial resistance.Journal of applied microbiology · 2022Review
- Cobalamin cbiP mutant shows decreased tolerance to low temperature and copper stress in Listeria monocytogenes.Biological research · 2022Article
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- Potential Probiotic Strains From Milk and Water Kefir Grains in Singapore-Use for Defense Against Enteric Bacterial Pathogens.Frontiers in microbiology · 2022Article
- Gene Analysis ofMicroorganisms · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Listeria monocytogenes is a virulent food-borne pathogen most often associated with the consumption of "ready-to-eat" foods. The organism is a common contaminant of food processing plants where it may persist for extended periods of time. A commonly used approach for the control of Listeria monocytogenes in the processing environment is the application of biocides such as quaternary ammonium compounds. In this study, the transcriptomic response of a persistent strain of L. monocytogenes (strain 6179) on exposure to a sub-lethal concentration of the quaternary ammonium compound benzethonium chloride (BZT) was assessed. Using RNA-Seq, gene expression levels were quantified by sequencing the transcriptome of L. monocytogenes 6179 in the presence (4 ppm) and absence of BZT, and mapping each data set to the sequenced genome of strain 6179. Hundreds of differentially expressed genes were identified, and subsequent analysis suggested that many biological processes such as peptidoglycan biosynthesis, bacterial chemotaxis and motility, and carbohydrate uptake, were involved in the response of L. monocyotogenes to the presence of BZT. The information generated in this study further contributes to our understanding of the response of bacteria to environmental stress. In addition, this study demonstrates the importance of using the bacterium's own genome as a reference when analysing RNA-Seq data.
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