ArticleTheScientificWorldJournal2014
Sex dependence of cognitive functions in bipolar disorder.
Article in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Relationships between cognition and daily functioning in adults with bipolar disorder: A systematic review and multilevel meta-analysis.Psychological bulletin · 2026Pooled it
- Domain-specific cognitive function in euthymic bipolar disorder: a systematic review and meta-analysis.Psychological medicine · 2025Pooled it
- Sex differences in psychosocial functioning and neurocognition in bipolar disorder: a systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- Structural Brain Network Alterations in Relation to Treatment and Illness Severity in Bipolar Disorder.Biological psychiatry · 2026Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of the present study was to assess the performance of lithium treated euthymic bipolar patients in tests measuring spatial working memory (SWM), planning, and verbal fluency and to delineate the influence of gender on cognitive functioning. Fifty-nine euthymic bipolar patients, treated with lithium carbonate for at least 5 yr, were studied. Patients and controls underwent a neuropsychological assessment. Bipolar patients had significantly worse results than the healthy controls in the spatial memory and planning as well as verbal fluency tests. We detected a gender-related imbalance in the SWM results. Deficits in SWM were observed in male-only comparisons but not in female-only comparisons. The SWM scores were significantly poorer in male patients than in male controls. In female-only comparisons, female patients did not have significantly poorer SWM results in any category than their controls. Bipolar women scored worse in some other tests. The present study points to the different patterns of neuropsychological disturbances in female and male patients and suggests that sex-dependent differences should be taken into account in order to tailor the therapeutic intervention aimed at the improvement of cognitive functions.
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Registered trials
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