Evidence map›Paper›PMID 24616577›Full record

ReviewJournal of Korean medical science2014

Cell therapy for wound healing.

Hi-Jin You, Seung-Kyu Han

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Journal of Korean medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03162367 phase2completednot on this mapstarted 2019, after this paper: background citation

Comparison Study OF Efficacy Of Autologous Epidermal Cell Suspension And Silver Sulfadiazine Ointment In Second Degree Burn

TypeinterventionalSponsorSCARM Institute, Tabriz, IranRan2019 to 2020Enrolled40ConditionsBurnArmsAutologous epidermal cell suspension, Silver sulfadiazine ointment
NCT03548610 nawithdrawnnot on this mapstarted 2019, after this paper: background citation

Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects: A Randomized, Controlled Study

TypeinterventionalSponsorBrigham and Women's HospitalRan2019 to 2021Enrolled0ConditionsWound of Skin, Non-melanoma Skin Cancer, Skin Graft Complications, Wound of Lower LegArmsNanofat-seeded biological scaffold on surgical defect
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hi-Jin YouDepartment of Plastic Surgery, Korea University College of Medicine, Seoul, Korea.ORCID 0000-0002-9997-2736
Seung-Kyu HanDepartment of Plastic Surgery, Korea University College of Medicine, Seoul, Korea.ORCID 0000-0002-2875-9276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In covering wounds, efforts should include utilization of the safest and least invasive methods with goals of achieving optimal functional and cosmetic outcome. The recent development of advanced wound healing technology has triggered the use of cells to improve wound healing conditions. The purpose of this review is to provide information on clinically available cell-based treatment options for healing of acute and chronic wounds. Compared with a variety of conventional methods, such as skin grafts and local flaps, the cell therapy technique is simple, less time-consuming, and reduces the surgical burden for patients in the repair of acute wounds. Cell therapy has also been developed for chronic wound healing. By transplanting cells with an excellent wound healing capacity profile to chronic wounds, in which wound healing cannot be achieved successfully, attempts are made to convert the wound bed into the environment where maximum wound healing can be achieved. Fibroblasts, keratinocytes, adipose-derived stromal vascular fraction cells, bone marrow stem cells, and platelets have been used for wound healing in clinical practice. Some formulations are commercially available. To establish the cell therapy as a standard treatment, however, further research is needed.

Indexed as

Wound HealingBlood PlateletsCell- and Tissue-Based TherapyDiabetes Mellitus, Type 2FibroblastsHumansKeratinocytesStromal CellsTissue EngineeringUlcerCell-and Tissue-based TherapyTissue EngineeringWounds and Injuries

Identifiers

PMID24616577
PMCPMC3945123

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.