ArticlePediatrics2014
National trends over 25 years in pediatric kidney transplant outcomes.
Article in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
What it found
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Who cites it
61 citing papers in PubMed, 208 citations in OpenAlex.
- Do Perioperative Surgical Factors Affect Early Graft Function in Pediatric Kidney Transplantation?Pediatric transplantation · 2026Article
- Pan-cancer polygenic risk score associates with cancer susceptibility following kidney transplantation.JCI insight · 2026Article
- One-year creatinine predicts long-term graft survival in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2026Article
- Risk Assessment of Delayed Graft Function in Pediatric Kidney Transplantation - a CERTAIN Research Network Analysis.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Article
- [The importance of sex/gender for graft and patient survival].Innere Medizin (Heidelberg, Germany) · 2025Review
- Drug Usage and Risk for Polypharmacy After Pediatric Solid Organ Transplantation-A National Register Study.Clinical transplantation · 2025Article
- Kidney Transplantation in Congenital Heart Disease Patients: What Are the Outcomes?Pediatric transplantation · 2025Article
- Donor-derived cell-free DNA testing in pediatric kidney transplant recipients: indications and clinical utility.Pediatric nephrology (Berlin, Germany) · 2025Article
- International validation of a pre-transplant risk assessment tool for graft survival in pediatric kidney transplant recipients.Clinical kidney journal · 2025Article
- Identifying Risk Factors for Graft Failure due to Chronic Rejection < 15 Years Post-Transplant in Pediatric Kidney Transplants Using Random Forest Machine-Learning Techniques.Pediatric transplantation · 2025Article
- Article
- Bortezomib for antibody-mediated rejection of kidney transplant in youth: Associations with donor-specific antibody.Pediatric transplantation · 2024Article
- Contraception in Medically Complex Adolescents and Young Adults.Open access journal of contraception · 2024Article
- "Weighing the Pros and Cons of Everything": A Qualitative Descriptive Study Exploring Perspectives About Living Donor Kidney Transplantation From Parents of Chinese Canadian Pediatric Patients With Chronic Kidney Disease.Canadian journal of kidney health and disease · 2024Article
- Clean Intermittent Catheterization in Children under 12 Years Does Not Have a Negative Impact on Long-Term Graft Survival following Pediatric Kidney Transplantation.Journal of clinical medicine · 2023Article
- Risk Factor Analysis for Long-Term Graft Survival Following Pediatric Kidney Transplantation: The Importance of Pretransplantation Time on Dialysis and Donor/Recipient Age Difference.Journal of clinical medicine · 2023Article
- Cytopenias in pediatric kidney transplant recipients: preceding factors and clinical consequences.Pediatric nephrology (Berlin, Germany) · 2023Article
- A pre-transplantation risk assessment tool for graft survival in Dutch pediatric kidney recipients.Clinical kidney journal · 2023Article
- Neurocognitive deficits may not resolve following pediatric kidney transplantation.Pediatric transplantation · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo investigate changes in pediatric kidney transplant outcomes over time and potential variations in these changes between the early and late posttransplant periods and across subgroups based on recipient, donor, and transplant characteristics.
methodsUsing multiple logistic regression and multivariable Cox models, graft and patient outcomes were analyzed in 17,446 pediatric kidney-only transplants performed in the United States between 1987 and 2012.
resultsTen-year patient and graft survival rates were 90.5% and 60.2%, respectively, after transplantation in 2001, compared with 77.6% and 46.8% after transplantation in 1987. Primary nonfunction and delayed graft function occurred in 3.3% and 5.3%, respectively, of transplants performed in 2011, compared with 15.4% and 19.7% of those performed in 1987. Adjusted for recipient, donor, and transplant characteristics, these improvements corresponded to a 5% decreased hazard of graft loss, 5% decreased hazard of death, 10% decreased odds of primary nonfunction, and 5% decreased odds of delayed graft function with each more recent year of transplantation. Graft survival improvements were lower in adolescent and female recipients, those receiving pretransplant dialysis, and those with focal segmental glomerulosclerosis. Patient survival improvements were higher in those with elevated peak panel reactive antibody. Both patient and graft survival improvements were most pronounced in the first posttransplant year.
conclusionsOutcomes after pediatric kidney transplantation have improved dramatically over time for all recipient subgroups, especially for highly sensitized recipients. Most improvement in graft and patient survival has come in the first year after transplantation, highlighting the need for continued progress in long-term outcomes.
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