Evidence map›Paper›PMID 24616124›Full record

ArticleMuscle & nerve2014

Sural sparing pattern discriminates Guillain-Barré syndrome from its mimics.

Angelika Derksen, Christian Ritter, Parveen Athar, Bernd C Kieseier, Pedro Mancias, Hans-Peter Hartung, Kazim A Sheikh, Helmar C Lehmann

Open access · greenAbstract read
In one paragraph

Article in Muscle & nerve, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 83 citations in OpenAlex.

  1. Guillain-Barré syndrome: a comprehensive review.European journal of neurology · 2024
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  16. Guillain-Barré syndrome mimics.Brain and behavior · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Angelika DerksenDepartment of Neurology, University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Christian Ritter
Parveen Athar
Bernd C Kieseier
Pedro Mancias
Hans-Peter Hartung
Kazim A Sheikh
Helmar C Lehmann
Heinrich Heine University Düsseldorf · DEForschungszentrum Jülich · DEUniversity Hospital Cologne · DE

Funding

Pathogenesis of Anti-ganglioside Antibody-Mediated NeuropathiesR01NS042888 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SHEIKH, KAZIM A · 2002 to 2016
$4.1M
NINDS NIH HHS R01 NS042888
6 · The paper itself

Abstract

introductionElectrodiagnostic features of demyelination are essential for establishing the diagnosis in demyelinating subtypes of Guillain-Barré syndrome (GBS), but they may also occur in disorders that mimic GBS clinically. Information about their frequency in GBS mimics is sparse.

methodsEvaluation of electrodiagnostic features from 38 patients with suspected GBS in whom the diagnosis was later refuted (GBS mimics). Their diagnostic accuracy was analyzed by comparison with nerve conduction studies (NCS) from 73 confirmed GBS patients.

resultsDisorders that mimicked GBS clinically at the time of hospital admission included other inflammatory, metabolic, toxic, or infectious neuropathies and spinal cord disorders. The sural sparing pattern was the most specific electrodiagnostic feature for demyelinating GBS.

conclusionsCommon electrodiagnostic abnormalities in early demyelinating GBS do not usually exclude other rare differential diagnoses. An exception to this is the sural sparing pattern described here, which strongly supports the diagnosis of demyelinating GBS.

Indexed as

Diagnosis, DifferentialAction PotentialsAdultAgedAged, 80 and overElectric StimulationElectrodiagnosisFemaleGuillain-Barre SyndromeHumansMaleMiddle AgedNeural ConductionPredictive Value of TestsRetrospective StudiesSural Nervedifferential diagnosisGBSGuillain-Barré syndromemisdiagnosisnerve conduction studiesperipheral neuropathy

Identifiers

PMID24616124
PMCPMC4431612
OpenAlexW1908583252

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.