Trial reportDigestive diseases and sciences2014
Can endoscopic ultrasound-guided fine needle aspiration offer clinical benefit for thick-walled gallbladders?
Trial report in Digestive diseases and sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic performance and safety of endoscopic ultrasound-guided tissue acquisition of gallbladder lesions: A systematic review with meta-analysis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Pooled it
- Contributions of endoscopic ultrasonography-guided tissue acquisition (EUS-TA) to the diagnostics of biliary stricture and gallbladder lesions.Journal of medical ultrasonics (2001) · 2024Review
- Recent Advances in Endoscopic Ultrasound for Gallbladder Disease Diagnosis.Diagnostics (Basel, Switzerland) · 2024Review
- The Role of Endoscopic Ultrasound in the Diagnosis of Gallbladder Lesions.Diagnostics (Basel, Switzerland) · 2021Review
- The Role of Fine Needle Aspiration Cytology in the Diagnosis of Gallbladder Cancer: A Systematic Review.Diagnostics (Basel, Switzerland) · 2021Review
- Effective Endoscopic Closure of Cholecysto-duodenal and Transverse Colon Fistulas Due to Squamous Cell Carcinoma of the Gallbladder Using Polyglycolic Acid Sheets and a Covered Metal Stent.Internal medicine (Tokyo, Japan) · 2021Article
- Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy.Journal of carcinogenesis · 2021Article
- Complications of Endoscopic Ultrasound-Guided Fine Needle Aspiration: A Narrative Review.Diagnostics (Basel, Switzerland) · 2020Review
- Histopathological Examination of Gallbladder Specimens in Kumaon Region of Uttarakhand.Journal of gastrointestinal cancer · 2020Article
- Predictive Factors for Inaccurate Diagnosis of Swollen Lymph Nodes in Endoscopic Ultrasound-Guided Fine Needle Aspiration.Clinical endoscopy · 2019Article
- The role of endoscopic ultrasound in the diagnosis of gallbladder diseases.Journal of medical ultrasonics (2001) · 2017Review
- Diagnosis and Treatment of Gallbladder Polyps: Current Perspectives.Euroasian journal of hepato-gastroenterologyReview
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo previous studies have compared cytology obtained under endoscopic transpapillary gallbladder drainage (ETGD) and EUS-guided fine needle aspiration (EUS-FNA) for thick-walled gallbladders.
aimThe present study investigated the diagnostic yield of bile cytology under ETGD and EUS-FNA for gallbladder tumors.
methodsA total of 69 patients were diagnosed as having gallbladder wall thickening. Among these patients, 28 patients were diagnosed by clinical follow-up, solely by imaging such as computed tomography or by histological examination of surgical specimens. The remaining 41 patients underwent ETGD and/or EUS-FNA. In these 41 patients, the clinical data collected included gender, age, diameter of gallbladder wall, site of gallbladder wall thickening, final diagnosis, adverse events, and diagnostic yield of ETGD and EUS-FNA.
resultsCyto-histological diagnosis with EUS-FNA was higher than that with ETGD, with a sensitivity of 100 versus 71%, specificity of 100 versus 94%, and accuracy of 100 versus 88%, respectively, in the two groups. In addition, the sampling adequacy of EUS-FNA was 100%. Adverse events were seen in five patients in the ETGD group (mild pancreatitis), although no adverse events were seen in the EUS-FNA group (P = 0.08).
conclusionOur results suggest that EUS-FNA can be safely performed for the diagnosis of gallbladder lesions. Further, this procedure may be the diagnostic method of choice over cytology of bile juice obtained via ETGD to obtain histological evidence of gallbladder cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.