Evidence map›Paper›PMID 24615225›Full record

ArticleJournal of biological physics2012

How simple can a model of an empty viral capsid be? Charge distributions in viral capsids.

Anže Lošdorfer Božič, Antonio Siber, Rudolf Podgornik

Abstract read
In one paragraph

Article in Journal of biological physics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Virus Isoelectric Point Estimation: Theories and Methods.Applied and environmental microbiology · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. IRAM: virus capsid database and analysis resource.Database : the journal of biological databases and curation · 2019
    Article
  15. Article
  16. The different faces of mass action in virus assembly.Journal of biological physics · 2018
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anže Lošdorfer BožičDepartment of Theoretical Physics, Jožef Stefan Institute, 1000, Ljubljana, Slovenia, anze.bozic@ijs.si.
Antonio Siber
Rudolf Podgornik

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigate and quantify salient features of the charge distributions on viral capsids. Our analysis combines the experimentally determined capsid geometry with simple models for ionization of amino acids, thus yielding a detailed description of spatial distribution for positive and negative charges across the capsid wall. The obtained data is processed in order to extract the mean radii of distributions, surface charge densities, as well as dipole moment densities. The results are evaluated and examined in light of previously proposed models of capsid charge distributions, which are shown to have to some extent limited value when applied to real viruses.

Indexed as

VirusesCapsidCucumovirusModels, MolecularProtein ConformationSurface Properties

Identifiers

PMID24615225
PMCPMC3473132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.