ArticleThe American journal of tropical medicine and hygiene2014
Safety of the combined use of praziquantel and albendazole in the treatment of human hydatid disease.
Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Medical treatment of cystic echinococcosis: systematic review and meta-analysis.BMC infectious diseases · 2018Pooled it
- Postoperative Prophylaxis of Cystic Echinococcosis with Albendazole and Praziquantel: A Retrospective Cohort Study.Biomedicines · 2026Article
- Cystic echinococcosis in Austria 2009-2024: national surveillance and two rare cases of musculoskeletal manifestations including clinical management strategies.BMC musculoskeletal disorders · 2026Article
- Comparison of the Effectiveness and Complications of PAIR, Open Surgery, and Laparoscopic Surgery in the Treatment of Liver Hydatid Cysts.Medicina (Kaunas, Lithuania) · 2025Article
- Ten-year experience with pediatric splenic Hydatidosis: Clinical profiles, surgical outcomes, and prognostic indicators.Food and waterborne parasitology · 2025Article
- Combination Therapy of Albendazole and Praziquantel for Treatment of Cardiac and Multiorgan Hydatid Cyst: A Case Report of Novel Treatment and Literature Review.Clinical case reports · 2024Article
- Follow up study of symptomatic human cystic echinococcosis treatment with albendazole and praziquantel, in Uruguay.BMC infectious diseases · 2024Article
- A Case Series and Literature Review of Alveolar Echinococcosis in Kashmir, India: An Emerging Endemic Zone forLife (Basel, Switzerland) · 2024Article
- Treatment of hepatic and pulmonary hydatidosis with albendazole and praziquantel.Helminthologia · 2023Article
- Adverse drug effects among students following mass de-worming exercise involving administration of Praziquantel and Albendazole in KEEA Municipality, Ghana.PLoS neglected tropical diseases · 2022Article
- Pulmonary embolism from cardiac hydatids.Indian journal of thoracic and cardiovascular surgery · 2021Article
- Evaluation of the efficacy of Zataria multiflora essential oil versus albendazole in patients infected with liver cystic echinococcosis: A nonrandomized clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Nanostructured lipid carriers of ivermectin as a novel drug delivery system in hydatidosis.Parasites & vectors · 2019Article
- Progress in the pharmacological treatment of human cystic and alveolar echinococcosis: Compounds and therapeutic targets.PLoS neglected tropical diseases · 2018Article
- Combination drug chemotherapy and massive skeletal allograft in the management of hydatid disease of femur.BMJ case reports · 2018Article
- Recurrence of cystic echinococcosis in an endemic area: a retrospective study.BMC infectious diseases · 2017Article
- Green chemical synthesis of gold nanoparticles by using Penicillium aculeatum and their scolicidal activity against hydatid cyst protoscolices of Echinococcus granulosus.Environmental science and pollution research international · 2017Article
- A Bystander Effect of Lung Cancer Chemotherapy on Chronic Echinococcal Disease.World journal of oncology · 2015Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is still no well-established consensus about the clinical management of hydatidosis. Currently, surgery continues to be the first therapeutic option, although treatment with anti-parasitic drugs is indicated as an adjuvant to surgery to decrease the number of relapses and hydatid cyst size. When surgery is not possible, medical treatment is indicated. Traditionally, albendazole was used in monotherapy as the standard treatment. However, combined therapy with albendazole plus praziquantel appears to improve anti-parasitic effectiveness. To date, no safety studies focusing on such combined therapy have been published for the treatment of hydatidosis. In this work, we analyze the adverse effects seen in 57 patients diagnosed with hydatidosis who were treated with praziquantel plus albendazole combined therapy between 2006 and 2010.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.