SynthesisPloS one2014
Efficacy of peer-led interventions to reduce unprotected anal intercourse among men who have sex with men: a meta-analysis.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- The effectiveness of peer-support for people living with HIV: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Peer education for HIV prevention among high-risk groups: a systematic review and meta-analysis.BMC infectious diseases · 2020Pooled it
- Effectiveness of peer-led interventions to increase HIV testing among men who have sex with men: a systematic review and meta-analysis.AIDS care · 2017Pooled it
- The impact of a syndemic theory-based intervention on HIV transmission risk behaviour among men who have sex with men in India: Pretest-posttest non-equivalent comparison group trial.Social science & medicine (1982) · 2022Trial
- Peer counselling versus standard-of-care on reducing high-risk behaviours among newly diagnosed HIV-positive men who have sex with men in Beijing, China: a randomized intervention study.Journal of the International AIDS Society · 2018Trial
- The influence of a peer-based HIV prevention intervention on conversation about HIV prevention among people who inject drugs in Baltimore, Maryland.AIDS and behavior · 2015Trial
- Peer support to improve the secondary distribution of Internet-based HIV self-testing kits among men who have sex with men in Zhuhai, China.Frontiers in public health · 2025Article
- Concordance of HIV Prevention Advocacy Reports and its Associations with HIV Protective Behaviors.AIDS and behavior · 2024Article
- Peer-based interventions to support transgender and gender diverse people's health and healthcare access: A scoping review.International journal of transgender health · 2024Article
- Supporting the helpers: what do peer deliverers of HIV interventions need to sustain their implementation efforts?Translational behavioral medicine · 2023Article
- Peer education interventions for HIV prevention and sexual health with young people in Mekong Region countries: a scoping review and conceptual framework.Sexual and reproductive health matters · 2022Article
- Attitudes Toward Peer-Delivered Sexual-Health Services Among New York City Sexual and Gender Minority Individuals Who Have Sex with Men and Attend Collective Sex Venues.Qualitative health research · 2022Article
- Peer Education and Peer Counselling for Health and Well-Being: A Review of Reviews.International journal of environmental research and public health · 2022Review
- Individual level peer interventions for gay and bisexual men who have sex with men between 2000 and 2020: A scoping review.PloS one · 2022Article
- Peer- and community-led responses to HIV: A scoping review.PloS one · 2021Article
- Sexual Risk Behaviors Associated with Sexually Transmitted Infections in a US Military Population Living with HIV After the Repeal of "Don't Ask, Don't Tell".AIDS patient care and STDs · 2020Article
- "Getting to Zero" Among Men Who Have Sex with Men in China: a Review of the HIV Care Continuum.Current HIV/AIDS reports · 2019Review
- Prevalence and correlates of alcohol and tobacco use among key populations in Togo in 2017: a cross-sectional study.BMJ open · 2019Article
- The Evidence Project risk of bias tool: assessing study rigor for both randomized and non-randomized intervention studies.Systematic reviews · 2019Article
- The Parasol Protocol: An Implementation Science Study of HIV Continuum of Care Interventions for Gay Men and Transgender Women in Burma/Myanmar.JMIR research protocols · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
objectiveTo conduct a systematic review and meta-analysis to evaluate the efficacy of peer-led interventions in reducing unprotected anal intercourse (UAI) among men who have sex with men (MSM).
methodsRandomized clinical trials (RCTs), quasi-experimental studies, pre- and post-intervention studies without control groups, and serial cross-sectional assessments involving peers delivering interventions among MSM and published as of February 2012 were identified by systematically searching 13 electronic databases and cross-referencing. Effect sizes (ES) were calculated as the changes of standardized mean difference (SMD) in UAI between groups or pre-post intervention.
resultsA total of 22 studies met the eligibility criteria, including five RCTs, six quasi-experimental studies, six pre-and-post intervention studies, and five serial cross-sectional intervention studies. We used 15 individual studies including 17 interventions for overall ES calculation; peer-led interventions reduced UAI with any sexual partners in meta-analysis (mean ES: -0.27; 95% confidence interval [CI]: -0.41, -0.13; P<0.01). Subgroup analyses demonstrated a statistically significant reduction on UAI in quasi-experimental studies (mean ES: -0.30; 95% CI: -0.50, -0.09; P = 0.01) and serial cross-sectional intervention studies (mean ES: -0.33; 95% CI: -0.57, -0.09; P = 0.01), but non-significant reduction in RCTs (mean ES: -0.15; 95% CI: -0.36, 0.07; P = 0.18) or pre- and post-intervention studies (mean ES: -0.29; 95% CI: -0.69, 0.11; P = 0.15). Heterogeneity was large across these 15 studies (I2 = 77.5%; P<0.01), largely due to pre-and-post intervention studies and serial cross-sectional intervention studies.
conclusionsPeer-led HIV prevention interventions reduced the overall UAI among MSM, but the efficacy varied by study design. More RCTs are needed to evaluate the effect of peer-led interventions while minimizing potential bias.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.