Evidence map›Paper›PMID 24614574›Full record

ArticlePloS one2014

Knee pain during strength training shortly following fast-track total knee arthroplasty: a cross-sectional study.

Thomas Bandholm, Kristian Thorborg, Troels Haxholdt Lunn, Henrik Kehlet, Thomas Linding Jakobsen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01729520 (Knee Joint Pain During Strength Training After Total Knee Arthroplasty), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01729520 nacompletednot on this map

Knee Joint Pain During Strength Training After Total Knee Arthroplasty: Effect of Loading and Repetitions to Failure

TypeinterventionalSponsorHvidovre University HospitalRan2012 to 2013Enrolled15ConditionsKnee OsteoarthritisArmsKnee extension strength training
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Thomas BandholmPhysical Medicine & Rehabilitation Research - Copenhagen (PMR-C), Department of Physical Therapy, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark; Clinical Research Centre, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Orthopedic Surgery, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
Kristian ThorborgPhysical Medicine & Rehabilitation Research - Copenhagen (PMR-C), Department of Physical Therapy, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Orthopedic Surgery, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark; Arthroscopic Center Amager, Amager Hospital, University of Copenhagen, Copenhagen, Denmark.
Troels Haxholdt LunnDepartment of Anaesthesiology, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark; Lundbeckfoundation Centre for Fast-track Hip and Knee Surgery, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
Henrik KehletLundbeckfoundation Centre for Fast-track Hip and Knee Surgery, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark; Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Thomas Linding JakobsenClinical Research Centre, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark; Lundbeckfoundation Centre for Fast-track Hip and Knee Surgery, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
Hvidovre Hospital · DKCopenhagen University Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLoading and contraction failure (muscular exhaustion) are strength training variables known to influence neural activation of the exercising muscle in healthy subjects, which may help reduce neural inhibition of the quadriceps muscle following total knee arthroplasty (TKA). It is unknown how these exercise variables influence knee pain after TKA.

objectiveTo investigate the effect of loading and contraction failure on knee pain during strength training, shortly following TKA.

designCross-sectional study.

settingConsecutive sample of patients from the Copenhagen area, Denmark, receiving a TKA, between November 2012 and April 2013.

participantsSeventeen patients, no more than 3 weeks after their TKA.

main outcome measuresIn a randomized order, the patients performed 1 set of 4 standardized knee extensions, using relative loads of 8, 14, and 20 repetition maximum (RM), and ended with 1 single set to contraction failure (14 RM load). The individual loadings (kilograms) were determined during a familiarization session >72 hours prior. The patients rated their knee pain during each repetition, using a numerical rating scale (0-10).

resultsTwo patients were lost to follow up. Knee pain increased with increasing load (20 RM: 3.1±2.0 points, 14 RM: 3.5±1.8 points, 8 RM: 4.3±2.5 points, P = 0.006), and repetitions to contraction failure (10% failure: 3.2±1.9 points, 100% failure: 5.4±1.6 points, P<0.001). Resting knee pain 60 seconds after the final repetition (2.7±2.4 points) was not different from that recorded before strength training (2.7±1.8 points, P = 0.88).

conclusionBoth loading and repetitions performed to contraction failure during knee- extension strength-training, increased post-operative knee pain during strength training implemented shortly following TKA. However, only the increase in pain during repetitions to contraction failure exceeded that defined as clinically relevant, and was very short-lived.

trial registrationClinicalTrials.gov NCT01729520.

Indexed as

Arthroplasty, Replacement, KneeResistance TrainingActivities of Daily LivingAgedCross-Sectional StudiesFemaleHumansKnee JointMaleMuscle ContractionPainWeight-Bearing

Identifiers

PMID24614574
PMCPMC3948740
OpenAlexW2109990360

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.